gms | German Medical Science

87th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

04.05. - 07.05.2016, Düsseldorf

Rare histological types of laryngeal cancer among the Bulgarian population

Meeting Abstract

  • corresponding author Lora Nikiforova - Division of Otorhinolaryngology, Department of Neurosurgery and ENT diseases, Me, Varna, Bulgaria
  • Nikolay Sapundzhiev - Division of Otorhinolaryngology, Department of Neurosurgery and ENT diseases, Me, Varna, Bulgaria
  • Ivan Krasnaliev - Department of Pathology, Medical University "Prof. Dr. P. Stoyanov", Varna, Bulgaria
  • Neli Zgurova - Department of Pathology, Medical University "Prof. Dr. P. Stoyanov", Varna, Bulgaria
  • Doroteya Malinova - Department of Pathology, Medical University "Prof. Dr. P. Stoyanov", Varna, Bulgaria

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 87. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Düsseldorf, 04.-07.05.2016. Düsseldorf: German Medical Science GMS Publishing House; 2016. Doc16hnod203

doi: 10.3205/16hnod203, urn:nbn:de:0183-16hnod2030

Published: March 30, 2016

© 2016 Nikiforova et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

Text

Introduction: The aim of this study was to evaluate the incidence of rare histological types and subtypes of laryngeal cancer, in a cohort of patients treated in the ENT Clinic “St. Marina” Hospital, Varna, Bulgaria.

Methods: A retrospective study of the medical records in a tertiary Head and Neck Surgery centre for a period of 6 years (between 2006 and 2012).

Results: A total of 258 patients with cancer of the larynx were identified. The percentage of squamous cell carcinoma (SCC) is 98% (253/258 cases). Of the patients with SCC 8 (3.2%) were basaloid SCCs. The other 245 (96.8%) were conventional SCCs with different stage of differentiation (G1- 50, G2-141, G3 -31, CIS – 7). Some rare types observed included small-cell carcinoma (1), adenocarcinoma (1), haemangiopericytoma (1), mucoepidermoid carcinoma (1), metastasis from clear renal cell carcinoma (1). The overall incidence of the rare histological types/metastases was 2% - 5/258 cases.

Conclusion: Our findings correspond to the data from the medical literature - over 90% of all laryngeal neoplasms are conventional SCCs. All of the rare histologies that we observe have been previously reported in literature and are with debatable etiology and treatment. They differ from the typical SCC in tumor behaviour, clinical presentation and progression.

The haemangiopericytoma, the small-cell carcinoma and the mucoepidermoid carcinoma are rare primary laryngeal tumors, whereas the adenocarcinoma can only be defined as primal if it cannot be specified otherwise. Laryngeal involvement of renal cell carcinoma is a very rare occurence.

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