Article
Eosinophile tissue infiltration as predictor in nasosinus mucous membrane disease
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Published: | March 26, 2015 |
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Outline
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Nasal polyp is, strictly speaking, hyperplastic mucous membrane of nose and sinuses. Based on epidemiological data several aethyopathogenesis theories had evolved, most common being infection and allergy. Both converge and diverge and have pros and cons of their own but both have several common factors that are implied, including eosinophiles, interleukine 6, VEGF and IgE.
Course of disease is frustrating both for clinician and patient.Thus, it is important to establish factors predictive to course of disease.
Aim of this paper is to examine weather number of tissue eosinophiles is predictive to gravity of disease and its tendency to relapse after surgery.
Study shall encompass 40 patients of both sexes and all ages.
Eosinophile infiltration shall be examined in vivo, prior to operation and postoperatively.
It is expected that greater eosinophile count contributes to gravity of disease.
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