Article
The state of paranasal sinuses in children with cystic fibrosis
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Published: | April 14, 2014 |
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Introduction: The world literature doesn’t contain much information concerning the state of paranasal sinuses in CF patients. There have been registered 105 patients with CF in the Republic of Belarus (with the population of 10 million people).
Materials and methods: 93 patients with different forms of CF underwent pediatric and otolaryngological examination. The youngest of them was 1.5 years of age and the oldest was 18. The diagnosis of all the patients was confirmed by DNA genetic investigation of their parents and the proband as well as by a positive sweat test that revealed an increased content of Na and Cl (more than 40 mmol/l).
Results: The purulent process of paranasal sinuses with viscous putty-like secretion was diagnosed in 19.3% of children (N=18), in 11 of them it was associated with a polypous process. CT data evidenced the total involvement of all the sinuses. 11 children underwent a surgery. The accumulation of thick, viscous, putty-like mucus between the polyps was marked. The results of the surgery were analyzed 5 years later. In all cases a recurrence of the disease was noted. It is possible that an aggressive course of the disease was associated with the presence of microscopic flora like Ps. Aeruginosa (N=7).
Conclusions: The children with CF should be followed up and treated by an otolaryngologist. A surgery on paranasal sinuses is aimed to eliminate a purulent infection focus that can result not only in increasing the life span but also improve the life quality of such patients.
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