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85th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

28.05. - 01.06.2014, Dortmund

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Etiological risk factors of glottic cancer, oncological and functional results of endoscopic laser cordectomy in a 7-year period

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  • corresponding author Dóra Pálinkó - University of Szeged Depart. of Otorhinolaryngolgy, Szeged, Hungary
  • Miklós Csanády - University of Szeged Depart. of Otorhinolaryngolgy, Szeged, Hungary
  • László Rovó - University of Szeged Depart. of Otorhinolaryngolgy, Szeged, Hungary

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 85. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Dortmund, 28.05.-01.06.2014. Düsseldorf: German Medical Science GMS Publishing House; 2014. Doc14hnod256

doi: 10.3205/14hnod256, urn:nbn:de:0183-14hnod2566

Published: April 14, 2014

© 2014 Pálinkó et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Introduction: The author analyzed the role of tobacco and alcohol consumption of 106 patients with early glottic cancer, who underwent endoscopic CO₂ laser cordectomy between 2004 and 2010. Oncological and preliminary functional results of the minimally invasive laser cordectomy are demonstrated.

Methods: The smoking and alcohol consumption habits are also presented in case control studies, which compare the patients with glottic cancer with a control group. Oncological results are analysed and retrospective evaluation of voice outcome was performed, including voice handicap index, telephone questionnaire and voice analysis.

Results: 78% of patients with vocal cord tumors was considered as smoker and 22% was not. In the control group 26% of the patients was found as smoker, but 74% was no smoker. The odds ratio showed that tobacco consumption (OR=10) increased the risk of glottic cancer’s development 10x, alcohol consumption (OR=2,7) 2,7x.

After primary laser excision 81% of the patients were healed, recurrences (19%) were treated: after repeated laser intervention for recurrences the oncological outcome of laser resection was 95% After salvage therapies (hemilaryngectomy, laryngectomy and radiation therapy) the function of larynx and the voice were preserved in 97% of the patients. The postoperative quality of voice was acceptable in 76% of the cases according to the questionnaire for patients. Subjective and objective phoniatric parameters showed correlation with the type of laser cordectomy.

Conclusions: Smoking and alcohol consumption may play remarkable role in the development of vocal cord cancers in our patients too. Good oncological results, quality of life and acceptable phonation can be achieved with endoscopic laser cordectomy.

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