Article
A 5-year epidemiological and pathological survey of papillary thyroid carcinoma
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Authors
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Rusmir Arslanagic
- ENT Clinic Sarajevo, Sarajevo, Bosnia
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Selma Arslanagic
- Sarajevo Clinical Center, Sarajevo, Bosnia
| Published: | April 14, 2014 |
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Outline
Text
In a 5-year time span a total of 41 patents with thyroid pappilary carcinoma was treated at ENT clinic of Sarajevo University. All patients underwent total thyroidectomy with neck dissection.Survey focused on major epidemiological and pathological characteristics of disease in order to examine trends of behaviour.
At 16 patients (39,1%) there was a solitary carcinoma present, at 25 (60,9%) it was adjoined with thyroid goiter, at 9 concomitant goiter and adenoma were present and at 5 patients (6,8%) concomitant Mb Hashimoto and Mb Basedow were present. One patient had both papillary and follicular carcinoma present in removed thyroid gland.
Median age was found to be 50, with females being afflicted more than males at 32 (78,1%) vs. 9 (21,9%). Median dimension of papillary carcinoma was found to be 1,67 cm. 20 (48,7%) were found to be papillary micro-carcinomas according to their size being less then 1 cm.
Intraglandular dissemination amongst micro-carcinomas was present at 26% whilst loco-regional metastasis was recorded at 21% of carcinomas. Larger carcinomas (more than 1 cm) gave intraglandular dissemination in 37% of cases and loco-regional metastasis in 33%.
Papillary microcarcinomas showed markedly less aggressive behavior compared to papillary carcinomas with less frequent intraglandular dissemination and metastasis..
Papillary carcinoma was more aggressive when recorded in younger individuals and of male gender.
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