gms | German Medical Science

88th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

German Society of Oto-Rhino-Laryngology, Head and Neck Surgery

24.05. - 27.05.2017, Erfurt

Intranasal trigeminal sensitivity in seasonal allergic rhinitis

Meeting Abstract

  • corresponding author Simona Negoias - HNO Klinik Inselspital Bern, Bern, Schweiz
  • Sara-Lynn Hool - HNO Klinik Inselspital Bern, Bern, Schweiz
  • Hergen Friedrich - HNO Klinik Inselspital Bern, Bern, Schweiz
  • Anna Gschwend - klinik für Allergologie, Rheumatologie und Immunologie Inselspital Bern, Bern, Schweiz
  • Milena Sokolowska - Schweizerisches Institut für Allergie- und Asthmaforschung, Davos, Schweiz
  • Marco-Domenico Caversaccio - HNO Klinik Inselspital Bern, Bern, Schweiz

Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. 88. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Erfurt, 24.-27.05.2017. Düsseldorf: German Medical Science GMS Publishing House; 2017. Doc17hno542

doi: 10.3205/17hno542, urn:nbn:de:0183-17hno5424

Published: April 13, 2017

© 2017 Negoias et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

Text

The study aimed at investigating the intranasal trigeminal sensitivity in patients with seasonal allergic rhinitis at 4 different points during the course of 1 year, correlating it to subjective airflow perception, allergic symptoms and endoscopic scores.

Sixteen subjects with birch or grass allergy planned to undergo allergen specific immunotherapy (30.1±6.8 years) and 20 healthy subjects (31.1±9.1years) were included. Intranasal trigeminal sensitivity was tested by means of CO2-thresholds with a standardized device. Sinonasal symptoms were asessed with SNOT-20 questionnaire while endoscopic findings were quantified using Lund-Kennedy-Score. Measurements began before allergy season and were performed every 3 Months. Data was analysed cross-sectional between groups and longitudinal within groups using nonparametric tests.

Before and during allergy season, no significant difference in trigeminal sensitivity, symptom or endoscopic scores was seen between groups, although patients with allergies showed a trend towards reduced trigeminal responsiveness before allergy season, possibly as a sign of chronic irritation. Further on, the distribution of the intranasal trigeminal sensitivity during the course of 1 year after initiation of allergen specific immunotherapy in patients as compared to healthy subjects will be discussed.

Der Erstautor gibt keinen Interessenkonflikt an.