gms | German Medical Science

Gesundheit – gemeinsam. Kooperationstagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), Deutschen Gesellschaft für Sozialmedizin und Prävention (DGSMP), Deutschen Gesellschaft für Epidemiologie (DGEpi), Deutschen Gesellschaft für Medizinische Soziologie (DGMS) und der Deutschen Gesellschaft für Public Health (DGPH)

08.09. - 13.09.2024, Dresden

Breaking Down Resistance: The Role of Antibiotic Stewardship in Pediatric Medicine

Meeting Abstract

  • Karen Holland - Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany
  • Sophie Diexer - Martin-Luther-Universität Halle-Wittenberg, Halle(Saale), Germany
  • Rafael Mikolajczyk - Martin-Luther University Halle-Wittenberg, Institute of Medical Epidemiology, Biostatistics and Informatics, Halle (Saale), Germany
  • Arne Simon - Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Homburg, Germany
  • Christian Dohna-Schwake - Universitätsklinikum Essen, Essen, Germany
  • Johannes Huebner - LMU Klinikum, Munich, Germany
  • Ulrich von Both - Ludwig-Maximilians-Universität München, Munich, Germany
  • Stefan Moritz - Universitätsklinikum Halle, Halle( Saale), Germany

Gesundheit – gemeinsam. Kooperationstagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), Deutschen Gesellschaft für Sozialmedizin und Prävention (DGSMP), Deutschen Gesellschaft für Epidemiologie (DGEpi), Deutschen Gesellschaft für Medizinische Soziologie (DGMS) und der Deutschen Gesellschaft für Public Health (DGPH). Dresden, 08.-13.09.2024. Düsseldorf: German Medical Science GMS Publishing House; 2024. DocAbstr. 528

doi: 10.3205/24gmds793, urn:nbn:de:0183-24gmds7931

Published: September 6, 2024

© 2024 Holland et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

Text

Introduction: With antibiotic resistance on the rise, addressing this issue in pediatric care has become more urgent than ever. The TELEKASPER stewardship program, with a focus on smart antibiotic practices—choosing the right drug, dose, and treatment length—is crucial. Our study explores these measures' impact on bacterial resistance patterns, aiming to refine treatment strategies for children's health.

Methods: The study encompasses pediatric clinics involved in the TELE-KASPER project across various German states from 2017 to 2023, collecting specific bacterial resistance data from clinical laboratories. We employed Generalized Additive Models (GAM) to analyze fluctuations and trends in resistance patterns, allowing for an adaptable examination of temporal and regional variations.

Results: The ongoing analysis seeks to identify trends in bacterial resistance within the stewardship framework, offering insights into the effectiveness of stewardship practices and informing recommendations for future interventions. A significant diversity in data recording practices was encountered, highlighting the need for standardized reporting to improve data interpretability and reliability.

Conclusion: Our findings emphasize the importance of innovative stewardship approaches in managing antibiotic resistance and the advantages of cohesive and well-coordinated strategies. There is a clear need for standardized data recording practices to enhance the quality and comparability of resistance data across regions and time.

The authors declare that they have no competing interests.

The authors declare that a positive ethics committee vote has been obtained.


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