Article
Quantitative ultrasound (QUS) measurement of the calcaneus in patients with long-term non-invasive mechanical ventilation (NIV)
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Authors
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Manfred Neuhauser
- Institut für Physikalische Medizin und Rehabilitation, GZW, Vienna, Austria
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Yvonne Pfündl
- Institut für Physikalische Medizin und Rehabilitation, GZW, Vienna, Austria
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Klaus Hohenstein
- Institut für Physikalische Medizin und Rehabilitation, GZW, Vienna, Austria
| Published: | October 24, 2011 |
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Outline
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Objective: Aim of the study was to examine whether persons with long-term non-invasive mechanical ventilation (NIV) show an increased fracture risk compared to the healthy collective. Quantitative ultrasound measurements allow a quantitative analysis of the bone status as well as an estimation of the fracture risk, similarly efficient as the DXA. Quantitative ultrasound measurements at the calcaneus in transversal transmission have been validated in comprehensive studies, amongst them also prospectively designed fracture studies.
Material/Methods: We examined 22 patients (9 male, 13 female), age average of 49 years (18–85 a), 60% of which are bed-ridden (13 patients), 27% mobile in a wheelchair (6 patients), 13% ambulatory, an average duration of stay of 22 months (2–81 months). The ultrasound measurements were carried out at the calcaneus using the Achilles Insight (GE Healthcare). Based on the Stiffness Index, the respective z-scores were collected.
Results: The mean z-score was -2,864 SD +/- 1,466 SD. Except one patient (z-score 0 SD), all showed a reduced z-score (z-score – 1,0 SD to – 4,5 SD). The younger the patients, the lower the results were (r -=0,646, p=0,046).
Conclusion: The existing results show that patients with NIV show a significantly increased fracture risk (p<0,05; r=0,646) compared to the healthy collective.
