gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Choroidal Neovascularisation associated with retinochoroidal coloboma: a case report

Meeting Abstract

  • corresponding author M. Spitzer - Department of Ophthalmology, Tübingen-University, Tübingen
  • F. Gelisken - Department of Ophthalmology, Tübingen-University, Tübingen
  • S. Grisanti - Department of Ophthalmology, Tübingen-University, Tübingen
  • D. Süsskind - Department of Ophthalmology, Tübingen-University, Tübingen
  • K. U. Bartz-Schmidt - Department of Ophthalmology, Tübingen-University, Tübingen

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogP 144

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Spitzer et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




Retinochoroidal colobomas are congenital abnormalities caused by incomplete closure of the embryonic fissure. Common complications of this malformation are cataracts and especially retinal detachments. Occasionally colobomas are associated with microphthalmia. Choroidal neovascularisation (CNV) secondary to retinochoroidal colobomas is a very rare finding.


A 28-year-old woman presented with decreased vision and metamorphopsia in the left eye in November 1994. Examination showed bilateral Iris and retinochoroidal colobomas. The best corrected visual acuity was 20/20 in the right eye and 20/400 in the left eye.


Funduscopic examination of the left eye revealed a subretinal, greyish, partly pigmented lesion at the border between the coloboma and normal retina. Fluorescein angiography of the left eye showed a subretinal leakage at the foveal edge of the retinochoroidal coloboma. The CNV was treated with laser photocoagulation. Follow-up visits up to ten years after the treatment with photocoagulation showed no new or relapsing CNV. The visual acuity of the left eye improved to 20/160.


Few cases of CNV secondary to retinochoroidal colobomas have been described in the literature. Typically, these CNVs arise at the juncture of the coloboma and the unaffected retina. In patients with a retinochoroidal coloboma complaing of decreased vision and metamorphopsia CNV should be considered as a differential diagnosis. Prompt photocoagulation may prevent further visual deterioration and stabilize visual function.