Article
Long-term refractive and visual outcome comparing penetrating keratoplasty only and the triple procedure in Fuchs' dystrophy
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Published: | September 22, 2004 |
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Outline
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Objective
To assess and compare the long-term refractive and visual outcome after penetrating keratoplasty (PK) only vs. the triple procedure in eyes with Fuchs' endothelial dystrophy.
Methods
Study design: retrospective, non-randomised, clinical, single centre study. 92 eyes were devided into Group 1 (28 eyes, which had undergone PK only, age: 62±13 years) and Group 2 (64 eyes, which had undergone the triple procedure, age: 69±10 years). In all eyes, a central trephination was performed (donor trephination from the epithelial side) using the 193 nm excimer laser along metal masks with 8 orientation teeth/notches. Hoffmann`s double-running cross stitch suture was applied in all eyes. Subjective refractometry, standard keratometry (Zeiss) and corneal topography analysis (TMS-1, Tomey) were performed. The results were compared between the two groups (Group 1 vs. Group 2) at various stages ("two sutures in"/"one suture out"/"two sutures out").
Results
Refractive cylinder [D] was 2.5/2.0/2.5 vs. 2.0/1.5/3.0, keratometric astigmatism [D] was 3.5/2.6/3.0 vs. 3.5/3.1/3.5. Keratometric central power [D] was 41.7/42.4/43.8 vs. 41.5/41.9/43.3 and topographic central power [D] was 42.3/43.6/43.7 vs. 42.6/41.8/44.3. The best- corrected visual acuity (BCVA) was 0.5/0.6/0.6 vs. 0.5/0.5/0.5. Spherical equivalent (SE) [D] was 0.0/0.0/-0.5 vs. -0.5/-0.5/-1.1. Surface regularity index (SRI) was 1.5/1.1/1.0 vs. 1.4/1.4/1.2 and surface asymmetry index (SAI) was 1.0/0.8/1.0 vs. 1.3/1.2/1.0. The proportion of regular and mild irregular keratometry mires was 44%/69%/68% vs. 29%/46%/66%. The differences between the two groups did not reach statistical significance at any of the stages.
Conclusions
Refractive and visual outcome after the triple procedure did not differ significantly from that after PK only. Therefore, we recommend the triple procedure in elderly patients with Fuchs`dystrophy and incipient cataract to avoid delayed visual rehabilitation and a second surgical procedure.