gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

10-year-results: Detection of long-term progressive optic disc changes using confocal laser tomography

Meeting Abstract

  • corresponding author H. Mueller - University of Freiburg, Department of Ophthalmology, Freiburg
  • A. Unsöld - University of Freiburg, Department of Ophthalmology, Freiburg
  • P. Maier - University of Freiburg, Department of Ophthalmology, Freiburg
  • S. Walter - Eye Clinic Augsburg, Augsburg
  • J. Funk - University of Freiburg, Department of Ophthalmology, Freiburg

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.06.02

The electronic version of this article is the complete one and can be found online at:

Published: September 22, 2004

© 2004 Mueller et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.




The detection of a slowly progredient loss of optic nerve fibres in patients with ocular hypertension is an important task in confocal laser tomography. We compared changes of the parameters of the Heidelberg Retina Tomograph with changes of static visual field measurements.


Since 1994, patients with ocular hypertension have been monitored prospectively. On average, every six months visual field measurements (Octopus 123, dG1x) as well as optic disc examinations using the HRT were performed. A progredient excavation of the optic nerve head was defined as an increasing or decreasing cohort of straight lines of the 66%-confidence interval of the linear regression line. We analysed the HRT-parameter Cup Area (CA), Cup Volume (CV), Cup Shape Measure (CSM) and Contour Height Variation (CHV) for the total disc and for six different sectors in 105 eyes (51 patients). A glaucomatous visual field defect and therewith the conversion from ocular hypertension (OHT) to open angle glaucoma (OAG) was defined by the appearance of a reproducible defect-cluster > 20 dB of two or three adjacent points.


Ten of 105 eyes converted from OHT to OAG. A significant linear increase of the global parameters occurred in 2 (CA), 4 (CSM), 1 (CV) and a decrease in 2 (CHV) eyes. The sectoral analysis improved the results of cup area and cup volume in the temporal superior and temporal inferior sectors (ts/ti): 5/4 (CA), 2/3 (CV). Cup shape measure showed slightly increased hits in the temporal superior, nasal (n) and nasal inferior (ni) sectors (5(ts), 6(n) 5(ni)).


The linear model for the progression of the optic disc parameters detected only a small amount of the converters. The hit rate could be increased with the sector based analysis. Cup shape measure showed the highest hit rate.