gms | German Medical Science

German Congress of Orthopedic and Trauma Surgery (DKOU 2017)

24.10. - 27.10.2017, Berlin

Platelet rich plasma for synovitis treatment in patients with haemophilia (PWH)

Meeting Abstract

  • presenting/speaker Horacio Caviglia - General Hospital Juan A. Fernandez, Haemophilia Argentinian Foundation, Caba, Argentina
  • María Landro - General Hospital Juan A. Fernandez, Caba, Argentina
  • Carla Daffunchio - General Hospital Juan A. Fernandez, Haemophilia Argentinian Foundation, Caba, Argentina
  • Ana Douglas Price - General Hospital Juan A. Fernandez, Caba, Argentina
  • Gustavo Galatro - General Hospital Juan A. Fernandez, Caba, Argentina
  • Daniela Neme - Fundacion de la Hemofilia, Caba, Argentina
  • Pablo Salgado - General Hospital Juan A. Fernandez, Caba, Argentina

Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017). Berlin, 24.-27.10.2017. Düsseldorf: German Medical Science GMS Publishing House; 2017. DocPO22-444

doi: 10.3205/17dkou769, urn:nbn:de:0183-17dkou7694

Published: October 23, 2017

© 2017 Caviglia et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

Text

Objectives: The Platelet rich plasma (PRP) has an anti-inflammatory action, and presence of chondrogenic factors. The aim of this study was to describe the effect of platelet rich plasma (PRP) injection in chronic synovitis of the joints in PWH.

Methods: Nineteen patients with 28 joints were treated between December 2014 - 2015. Eighteen were Haemophilia type A (17 severe, 1 mild) and 1 type B severe. Mean age was 26 years old. Chronic synovitis were presented in 2 (7,1%) ankles, 7 (25%) elbows and 19 (67,9%) knees joints. Patients were evaluated in every target joint: range of motion (ROM), perimeter, Haemophilia Joint Health Score (HJHS), number of bleedings in the last 30 days, Visual Analogue Scale (VAS); before, three and six months after treatment.

Results and Conclusion: A mean volume of 4 ml of PRP were injected into the joint. The HJHS pre and post treatment was statistical significant (p<0.001). Decrease of joint bleeding episodes was statistically significant (p<0.001). All patients reported pain relief and has been found statistically significant for the VAS-scores (p<0.001). The whole joint perimeter measures evidence a statistically significant difference (p<0.001). No complications were shown in none of the patients, in blood collection or PRP injection.