Article
CRP levels and functional performance after total knee arthroplasty
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Published: | October 13, 2014 |
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Aim: To determine the correlation between functional status and CRP levels, after knee arthroplasty.
Methods/subjects: In a prospective study, 57 patients (17 males and 40 females, age 62±5.6 ys) undergoing total knee arthroplasty for knee osteoarthritis treatment, were included. Serum CRP levels were measured at second postoperative day after total knee arthroplasty performed. Functional performance was measured with the Knee Society Score (KSS) and Western Ontario and McMaster Universities Index (WOMAC) at baseline, 1 month, 6 months and 1 year after the total knee arthroplasty. Patients experienced complications were excluded. Statistical analysis was performed by statistical packet STATA 8.0. Many factors such as age, gender, ASA score, grade of osteoarthritis, duration of symptoms, Hgb levels, alboumin levels, BMI, were included in a regression analysis model. Significance was set at p-value <0.05.
Results: The mean postoperative serum CRP level was 6.98±2.6 g/L. Significant correlations were found between CRP levels and KSS (r=-0.85, p=0.03) and WOMAC scores (r=-0.78, p=0.047) at the first month, between CRP levels and KSS and WOMAC scores at 6 months (r=-0.81, p=0.03 and r=-0.82, p=0.025 respectively) but found no correlation at 1 year (r=0.15, p=0.73 and r=0.11, p=0.19 respectively) postoperatively.
Conclusion: CRP levels are useful short term prognostic factors of functional performance after total knee arthroplasty.