Article
Aneurysm architecture – first in vivo imaging of human cerebral aneurysms with extravascular optical coherence tomography
Die Architektur von Aneurysmen – die ersten in vivo Darstellungen zerebraler Aneurysmen mittels extravaskulärer, optischer Kohärenztomographie
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Published: | June 4, 2021 |
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Objective: The present study explores three-dimensional microscope integrated extravascular OCT as the first suitable intraoperative imaging modality of cerebral aneurysm (CA) and parent vessel wall morphology.
Methods: Incidental CAs (n=16) of the anterior circulation with indication for microsurgical clipping were scanned.
Results: Analysis revealed that intraoperative OCT achieved to delineate the microstructural composition of the parent vessel in all cases and the CA wall in 68,8 %. Clinical relevant characteristics like thickness, calcification, residual tunica media and atherosclerotic plaque of CA wall could be demonstrated with high image quality approaching spatial resolution of histopathology.
Conclusion: Our findings demonstrate that intraoperative OCT may hold promise as an additional imaging tool during neurovascular procedures.
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