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72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

06.06. - 09.06.2021

Does physical activity undertaken by people with CNS cavernomas provoke the onset of the disease?

Verursacht körperliche Aktivität von Menschen mit ZNS-Kavernomen den Ausbruch der Krankheit?

Meeting Abstract

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  • presenting/speaker Loay Shoubash - Universitätsmedizin Greifswald, Greifswald, Deutschland
  • Sascha Marx - Universitätsmedizin Greifswald, Greifswald, Deutschland
  • Henry W. S. Schroeder - Universitätsmedizin Greifswald, Greifswald, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie. sine loco [digital], 06.-09.06.2021. Düsseldorf: German Medical Science GMS Publishing House; 2021. DocP163

doi: 10.3205/21dgnc445, urn:nbn:de:0183-21dgnc4458

Published: June 4, 2021

© 2021 Shoubash et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at



Theories that suggest that certain activities pose a risk to patients with cavernomas are not supported by clinical studies.

Objective: To assess the relationship between the physical activity state in the last one hour and the onset of the first symptoms in people harboring cavernoma.

Methods: A monocentric retrospective conducted study in patients that were surgically treated between the years 2005 and 2019 in a tertiary hospital. 52 of 81 patients had been interviewed between January 2017 to January 2020. 34 patients included in the study. The authors evaluated the incidence of cavernoma following physical activity.

Results: The study included 20 females (58.9%) and 14 males (41.1%), the mean age at onset was 38.1 years (F: 39.4, M:36.5). The symptomatic cavernoma was 24 in supratentorial (70.6%), 4 in the cerebellum (11.8%), 4 in the brainstem (11.8%), one in the spinal cord (2.9%), and the last in the orbital region (2.9%).

Of the 34 subjects, 30 patients (88.2%) reported the onset of the disease followed a light activity or no active state, only 3 cases (8.8%) reported having engaged in a moderate activity during the hour before cavernoma onset, and the last under emotional stress.

Conclusion: We concluded that physical activity in the last hour likely does not evoke the onset of the disease in patients harboring CNS cavernomas, as the cavernous malformation is a passive capillary anomaly.

Figure 1 [Fig. 1], Figure 2 [Fig. 2]