gms | German Medical Science

72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

06.06. - 09.06.2021

Automated screw planning of navigated lumbosacral pedicle screws using artificial intelligence

Vollautomatische Planung navigierter lumbosakraler Pedikelschrauben mittels künstlicher Intelligenz

Meeting Abstract

  • presenting/speaker Moritz Scherer - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Lisa Kausch - DKFZ Heidelberg, Medical Image Computing, Heidelberg, Deutschland
  • Basem Ishak - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Alexander Younsi - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Karl Kiening - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Martin Bendszus - Universitätsklinikum Heidelberg, Neuroradiologie, Heidelberg, Deutschland
  • Jan-Oliver Neumann - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Klaus Maier-Hein - DKFZ Heidelberg, Medical Image Computing, Heidelberg, Deutschland
  • Andreas W. Unterberg - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie. sine loco [digital], 06.-09.06.2021. Düsseldorf: German Medical Science GMS Publishing House; 2021. DocV130

doi: 10.3205/21dgnc123, urn:nbn:de:0183-21dgnc1232

Published: June 4, 2021

© 2021 Scherer et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.


Outline

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Objective: Use of navigation for spinal instrumentation has gained traction in recent years but preoperative trajectory-planning is a time-consuming task. We sought to develop and validate an automated planning tool for lumbosacral pedicle screws using a convolutional neural network (CNN).

Methods: We used planning data from random 155 CT-navigated instrumentations and extracted screw parameters from 1052 pre-planned pedicle screws covering L2-S1 levels, which served as training data for a CNN. A vertebra instance-based approach employing a state-of-the-art U-Net framework was developed and trained followed by internal 5-fold cross-validation. The retrieved net was evaluated on an external test-set of 30 cases not involved in training. Automatic screw parameters were compared to corresponding pre-planned screws in the test-set by mean absolute difference (MAD) of screw head and tip points, length and diameter, respectively. Clinical acceptability of algorithm-generated screws was evaluated by experts using the Gertzbein-Robbins (GR) classification.

Results: Automated planning was feasible for all targeted 198 screws. Compared to pre-planned screws, MAD was 4.3±2.1mm for screw head, 4.2±2.4mm for tip points, 4.6±3.1mm for length and 0.4±0.3mm for diameter. In ANOVA followed by Dunn’s multiple comparison, MAD for head and tip points was significantly greater at L5 and S1 compared to other segments (p<0.001), reflecting increasing degrees of freedom in caudal screw placement. No difference between segments was found for screw length and diameter. Upon expert rating, screws were predominantly classified grade A (189, 95%) with only 9 grade B screws (5%) according to GR indicating that screws showed either no, or only minor (<2mm) cortical breach. All planned screws were classified clinically acceptable. Algorithm generated screws were not inferior to their manually planned companions.

Conclusion: We derived a fully automated planning tool for lumbosacral pedicle screws using CNN. Validation showed sufficient accuracy to facilitate screw planning with high potential to increase time-efficiency in navigated spinal instrumentation when integrated into commercial navigation systems.