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71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

21.06. - 24.06.2020

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Safety and feasibility of resection of brain metastases combined with intraoperative radiotherapy – a single-centre experience with 34 cases

Sicherheit und Resektabiliät von Hirnmetastasen kombiniert mit intraoperativer Radiotherapie – eine monozentrische Studie mit 34 Fällen

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  • presenting/speaker Sebastian Ertl - Universitätsklinikum Augsburg, Klinik für Neurochirurgie, Augsburg, Deutschland
  • Henning Kahl - Universitätsklinikum Augsburg, Klinik für Strahlentherapie, Augsburg, Deutschland
  • Nikolaos Balagiannis - Universitätsklinikum Augsburg, Klinik für Strahlentherapie, Augsburg, Deutschland
  • Georg Stüben - Universitätsklinikum Augsburg, Klinik für Strahlentherapie, Augsburg, Deutschland
  • Ute Grossert - Universitätsklinikum Augsburg, Klinik für Neurochirurgie, Augsburg, Deutschland
  • Volkmar Heidecke - Universitätsklinikum Augsburg, Klinik für Neurochirurgie, Augsburg, Deutschland
  • Ehab Shiban - Universitätsklinikum Augsburg, Klinik für Neurochirurgie, Augsburg, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie. sine loco [digital], 21.-24.06.2020. Düsseldorf: German Medical Science GMS Publishing House; 2020. DocP058

doi: 10.3205/20dgnc346, urn:nbn:de:0183-20dgnc3468

Published: June 26, 2020

© 2020 Ertl et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

Outline

Text

Objective: The utility of intraoperative radiotherapy (IORT) has been demonstrated in many and diverse surgical fields. However, data for the utility for brain metastases (BrM) is scarce.

Methods: A retrospective study of nonconsecutive patients following surgical resection and IORT of BrM between January 2013 and October 2019 was performed. Surgical and oncological outcome was evaluated.

Results: 34 patients were identified. 56% were female. Median age was 61 (range 39 – 82). Breast cancer was the most common primary and was found in 26% of cases. IORT delivered a mean of 20 Gy (Range 13 – 20). Mean follow up was 8 months (range 1 -60).Local tumor control was seen in 82% of all cases. Surgical complications were seen in 15% of cases (2 neurological deterioration, 2 wound healing disorder and one case of postoperative hemorrhage).

Conclusion: IORT is a safe and effective method to achieve sustainable local tumor control for patients with brain metastases.