Article
Surgery for cervical spondylotic myelopathy – when to operate?
Operative Therapie der zervikalen Myelopathie – Wann sollten wir operieren?
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Published: | June 26, 2020 |
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Outline
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Objective: Cervical spondylotic myelopathy (CSM) is the most common reason for spinal cord injuries in elderly patients. Up to now, timing of surgical treatment is still various.
In this study we analysed demographic data, comorbidities, surgical treatment, number of treated levels and radiological findings such as high signal intensity (SI) on MRI to evaluate the association on the postoperative neurological outcome.
Methods: Patients treated in our department between 2007 until 2016 with CSM were analysed retrospectively. The modified Japanese Orthopaedic Association Score (mJOA), the mJOA Score improvement and the Minimum Clinically Important Difference (MCID) were used to define the pre- and postoperative neurological function. Multivariate Analysis was performed for sex, age, comorbidities, high SI on MRI, surgical approach.
Results: The study group comprised 411 (36.0 % female, mean age: 62.6 years (range: 31 - 96years). Surgical treatment and the number of treated levels did not influence the postoperative outcome. There was a significant improvement of the functional study endpoints after evaluation of the postoperative mJOA Score and the MCID (p < 0.001). In the multivariate analysis, patients’ age, CCI and high SI on T2-weighted MRI (p=0.0005) were independently associated with a lower pre- and postoperative mJOA Score and the lower postoperative MCID.
Conclusion: Surgical treatment and the number of treated levels did not affect the neurological outcome. Age, Comorbidities, high SI on MRI are negatively associated with the preoperative status and the postoperative neurological outcome (postoperative mJOA Score and MCID). Therefore, surgery should be performed before a high SI on MRI is present to prevent irreversible damage of the spinal cord.