gms | German Medical Science

71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

21.06. - 24.06.2020

Article

Send article

Quantitative assessment of intraneural vascular alterations in peripheral nerve trauma using high-resolution neurosonography – technical note

Quantitative Erfassung vaskulärer Veränderungen in traumatisch geschädigten peripheren Nerven mit Hochfrequenz-Neurosonographie

Meeting Abstract

Search Medline for

  • presenting/speaker Christian Heinen - Evangelisches Krankenhaus Oldenburg, Universitätsklinik für Neurochirurgie, Oldenburg, Deutschland
  • Thomas Kretschmer - Klinikum Klagenfurt am Wörthersee, Neurochirurgie, Klagenfurt, Austria
  • Ulrike Janssen-Bienhold - Carl von Ossietzky Universität Oldenburg, Visuelle Neurowissenschaft, Oldenburg, Deutschland
  • Johannes Woitzik - Evangelisches Krankenhaus Oldenburg, Universitätsklinik für Neurochirurgie, Oldenburg, Deutschland
  • Bettina Kewitz - Carl von Ossietzky Universität Oldenburg, Visuelle Neurowissenschaft, Oldenburg, Deutschland
  • Patrick Dömer - Carl von Ossietzky Universität Oldenburg, Visuelle Neurowissenschaft, Oldenburg, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie. sine loco [digital], 21.-24.06.2020. Düsseldorf: German Medical Science GMS Publishing House; 2020. DocV292

doi: 10.3205/20dgnc288, urn:nbn:de:0183-20dgnc2881

Published: June 26, 2020

© 2020 Heinen et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.

Outline

Text

Objective: High-resolution neurosonography (HRNS) has become a major imaging modality in assessment of peripheral nerve trauma in the recent years. However, only little attention was given to the assessment of vascular changes of such lesions in HRNS. Here, we describe the quantitative assessment of intraneural vascular alterations in patients.

Methods: N=9 patients suffering from peripheral nerve trauma were examined clinically, electrophysiologically and with HRNS (SonoSite Exporte, Fuji). Image analyses using Fiji included determination of the established fascicular ratio (FR), the cross-section ratio (CSR), and as an extension, the calculation of a vascular ratio (VR) of healthy versus damaged nerve and a muscle perfusion ratio (MPR) in comparison to a healthy control group.

Results: The mean VR in the healthy part of the affected nerve (14.14%) differed significantly (p < 0.0001) from the damaged part (VR of 43.26%). This coincides with significant differences in the FR and CSR calculated for the damaged part versus the healthy part and the controls. In comparison, there was no difference between VRs determined for the healthy part of the affected nerve and the healthy controls (14.14% / 17.72%). However, the MPR of denervated muscles was significantly decreased compared to the non-affected contralateral controls.

Conclusion: VR and MPR serve as additional tools in assessing peripheral nerve trauma. Image analysis and calculation are feasible. Combined with the more morphologic FR and CSR the VR and MPR provide a more detailed insight into alterations accompanying nerve trauma.