gms | German Medical Science

67th Annual Meeting of the German Society of Neurosurgery (DGNC)
Joint Meeting with the Korean Neurosurgical Society (KNS)

German Society of Neurosurgery (DGNC)

12 - 15 June 2016, Frankfurt am Main

The pattern of spread and histopathology in multiple meningiomas

Meeting Abstract

  • Woo Youl Jang - Chonnam National University Hwasun Hospital, Korea
  • Shin Jung - Chonnam National University Hwasun Hospital, Korea
  • Tae-Young Jung - Chonnam National University Hwasun Hospital, Korea
  • Kyung-Sub Moon - Chonnam National University Hwasun Hospital, Korea
  • In-Young Kim - Chonnam National University Hwasun Hospital, Korea

Deutsche Gesellschaft für Neurochirurgie. 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS). Frankfurt am Main, 12.-15.06.2016. Düsseldorf: German Medical Science GMS Publishing House; 2016. DocMO.06.06

doi: 10.3205/16dgnc032, urn:nbn:de:0183-16dgnc0320

Published: June 8, 2016

© 2016 Jang et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at



Objective: Multiple meningiomas are defined as at least two spatially separated meningiomas occurring simultaneously or more than two meningiomas arising sequentially from two clearly distinct regions. We reviewed the radiological findings, pathological diagnosis, and clinical outcome of multiple meningiomas.

Method: Between 2004 and 2015, 62 patients with multiple meningiomas underwent microsurgical resection in our institute. Multiple meningiomas were classified based on the pattern of spread. If the tumor is located adjacent to another tumor and the distance between tumors are less than 5 mm, the pattern of spread is defined as contiguous pattern. Histopathological study was performed, specially focused on the meninges between tumors.

Results: In 15 patients, tumors spread contiguously via the meninges pattern. Among them, 7 patients had separated noncontiguous meningiomas accompany with contiguous meningiomas. All of contiguous meningiomas showed same pathology. It is histopathological confirmed that there was the trail between tumors in contiguous meningiomas. Other 47 patients had noncontiguous meningiomas and the pathologies were different each other in 8 patients.

Conclusions: The pathogenesis of multiple meningiomas is different according to the spreading pattern. The contiguous meningiomas can spread more widely through the meninges and required radiological study should be performed more frequently than noncontiguous meningiomas.