gms | German Medical Science

57th Annual Meeting of the German Society of Neurosurgery
Joint Meeting with the Japanese Neurosurgical Society

German Society of Neurosurgery (DGNC)

11 - 14 May, Essen

Article

Send article

There seems to be no correlation between subarachnoid hemorrhage related vasospasm and the chart of platelets in a Caucasian population

Es scheint keine Korrelation zwischen dem Vasospasmus nach Subarachnoidalblutung und dem Thrombozytenverlauf in einer kaukasischen Population zu geben

Meeting Abstract

Search Medline for

  • corresponding author K. Schebesch - Klinik für Neurochirurgie der Universität Regensburg
  • R. Rothoerl - Klinik für Neurochirurgie der Universität Regensburg
  • C. Woertgen - Klinik für Neurochirurgie der Universität Regensburg
  • A. Brawanski - Klinik für Neurochirurgie der Universität Regensburg

Deutsche Gesellschaft für Neurochirurgie. Japanische Gesellschaft für Neurochirurgie. 57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie. Essen, 11.-14.05.2006. Düsseldorf, Köln: German Medical Science; 2006. DocP 09.131

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dgnc2006/06dgnc348.shtml

Published: May 8, 2006

© 2006 Schebesch et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Objective: There has been a most controverse discussion about the etiology and pathophysiology of subarachnoid hemorrhage (SAH) related vasospasm in the last decade. Several pathogenic factors like endothelin, adhesion molecules etc. have been discussed. A recently published study concerning an exclusively Asian population suggested the relationship between the SAH related vasospasm and the amount, respectively the chart of platelets. Aim of this study was to examine this relationship in a European population.

Methods: We carefully reviewed 88 patients with aneurysmal SAH (54 female, 34 men; mean age 52.5 years, range from 22 to 78 years) treated in our centre with regard to occurrence of vasospasm and the values of platelets in a ten days inteval after initial SAH; symptomatic vasospasm was defined as a focal neurological deficit or deterioration in the level of consciousness with either confirmation of infarction on a CT scan. 37 patients (42%) developed a clinical relevant vasospasm.

Results: There was neither statistical significant correlation between the chart or the amount (maximum and minimum value) of platelets and vasospasm or clinical outcome; we also found no gender or age-related influence on the above mentioned relationships.

Conclusions: To our opinion it seems that there is a difference between a Caucasian and an Asian population regarding the influence of platelets in the pathophysiology of SAH and vasospasm.