gms | German Medical Science

57th Annual Meeting of the German Society of Neurosurgery
Joint Meeting with the Japanese Neurosurgical Society

German Society of Neurosurgery (DGNC)

11 - 14 May, Essen

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Development of ion beam irradiated ePTFE as the best wrapping material for the treatment of the unclippable cerebral aneurysms

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  • corresponding author K. Katopu - Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University, Tokyo, Japan; Division of Surface of Characterization, The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan
  • H. Ujiie - Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University, Tokyo, Japan; Division of Surface of Characterization, The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan
  • Y. Suzuki - Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University, Tokyo, Japan; Division of Surface of Characterization, The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan
  • N. Takahashi - Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University, Tokyo, Japan; Division of Surface of Characterization, The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan
  • T. Yotoriyama - Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University, Tokyo, Japan; Division of Surface of Characterization, The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan
  • T. Hori - Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University, Tokyo, Japan; Division of Surface of Characterization, The Institute of Physical and Chemical Research, Wako-shi, Saitama, Japan

Deutsche Gesellschaft für Neurochirurgie. Japanische Gesellschaft für Neurochirurgie. 57. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie. Essen, 11.-14.05.2006. Düsseldorf, Köln: German Medical Science; 2006. DocP 02.20

The electronic version of this article is the complete one and can be found online at: http://www.egms.de/en/meetings/dgnc2006/06dgnc237.shtml

Published: May 8, 2006

© 2006 Katopu et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Objective: Wrapping is frequently used when clipping of aneurysms is thought to be impossible due to the broad neck or to be unsafe for perforating arteries. Furthermore, reinforcement of the aneurysm wall of the dog ear remnant at neck clipping is routinely necessary in aneurysm surgery. However, since wrapping does not eliminate the aneurysm, the risk of rebleeding and regrowth of aneurysms is left after surgeries. In these procedures, various wrapping materials have been used, including muscle fascia, muslin, Gore-Tex, and Silastic sheet. However no completely ideal wrapping material was reported before.

Results: We have developed ion beam irradiated expanded polytetrafluoroethylene (ePTFE) sheets for wrapping that shows firm and inert characteristics with strong cell adhesion. Ion beam irradiation is noticed to produce an improvement of polymer surfaces such as ePTFE.

Conclusions: In this report, we introduced the in-vivo and in-vitro experimental study of the newly developed ion beam irradiated ePTFE as well as clinical experiences for skull base surgeries.