gms | German Medical Science

130. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

30.04. - 03.05.2013, München

Hepatic hemodynamic changes after stepwise liver resection

Meeting Abstract

  • Mohammad Golriz - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Saroa Elsakka - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Arman Edalatpour - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Mohammadreza Hafezi - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Nahid Rezaei - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Camelia Garoussi - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Jalal Arwin - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Koosha Gazi Moghadam - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Arash Saffari - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Hanna Raisi - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Azadeh Fallahi - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Arezou Abbasi - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Hamidreza Fonouni - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Arash Nickkholgh - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg
  • Arianeb Mehrabi - Heidelberg, Allgemein-, Viszeral- und Transplantationschirurgie, Heidelberg

Deutsche Gesellschaft für Chirurgie. 130. Kongress der Deutschen Gesellschaft für Chirurgie. München, 30.04.-03.05.2013. Düsseldorf: German Medical Science GMS Publishing House; 2013. Doc13dgch723

doi: 10.3205/13dgch723, urn:nbn:de:0183-13dgch7235

Published: April 26, 2013

© 2013 Golriz et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.


Outline

Text

Introduction: Extended liver resection has increased during the last decades. However, hepatic hemodynamic changes after resection and the consequent complications like small for size syndrome are still a challenging issue. The aim of this study was to systematically evaluate the role of sequential liver resection on hepatic hemodynamic changes.

Material and methods: To evaluate this effect we performed 25, 50 and 75 % sequential liver resections in 8 pigs. Before and after each resection the flow of the hepatic artery (HAF) and portal vein (PVF) in relation to the 100 gram remnant liver as well as pressure of the portal vein (PVP) were measured and compared between the groups.

Results: Following sequential liver resection, the total hepatic inflow (HAF PVF) increases gradually. In details, the HAF decreases 17% and PVF increases 73% after extended liver resection (75%). Also, with sequential liver resection, the PVP increases gradually up to 33% after extended liver resection (75%).

Conclusion: Seq uential increase in the liver resection volume decreases the HAF/min/100g and increase the PVF/min/100g and PVP. This results in a THF with poorer O2 blood supply and higher pressure. This phenomenon can explain the mechanism of the postoperative complications of small for size syndrome, which lead to liver failure.