gms | German Medical Science

28. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2010)

13.01. bis 16.01.2010, Schladming, Österreich

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Suprathel®-Acetic-Acid-Matrix versus Acticoat® and Aquacel® as an antiseptic dressing – an in-vitro study

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  • corresponding author H. Ryssel - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany
  • M. Otte - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany
  • G. Germann - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany
  • K. Riedel - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany
  • M. Reichenberger - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany
  • S. Hellmich - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany
  • O. Kloeters - Department of Hand-, Plastic and Reconstructive Surgery – Burn Center – BG Trauma Center, Ludwigshafen, Germany

DAV 2010. 28. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung. Schladming, Österreich, 13.-16.01.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10dav07

doi: 10.3205/10dav07, urn:nbn:de:0183-10dav078

Published: June 30, 2010

© 2010 Ryssel et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Background: The treatment of burn wounds is still a challenge concerning the management of antiseptic treatment. Especially in the United States silver containing dressings such as Acticoat® and Aquacel® are frequently used. Because silver containing dressings have well known drawbacks like a therapeutical lack in Pseudomonas aeruginosa we searched for an alternative dressing. In prior studies we showed the excellent antiseptic activity of acetic acid against common burn unit germs and in another study the feasibility and suitability of a Suprathel®-Acetic-Acid-Matrix as an antiseptic dressing.

Materials/Methods: This study was designed to test the in-vitro antimicrobial effect of a “Suprathel®- Acetic-Acid -Matrix” versus Acticoat® and Aquacel®. To cover the typical bacterial spectrum of a burn unit, the following gram-negative and gram-positive bacteria strains were tested: Escherichia coli, ESBL-positive Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, Enterococcus faecalis, methicillin-resistent Staphylococcus aureus (MRSA).

Results: The tests showed an excellent bactericidal effect of the “Suprathel®-Acetic-Acid-Matrix” particularly with problematic gram-negative bacteria such as Proteus vulgaris, Pseudomonas aeruginosa and Acinetobacter baumanii. The efficiency was superior to that of Acicoat® and Aquacel®.

Conclusion: It can be concluded, that “Suprathel®-Acetic-Acid-Matrix” has an excellent bactericidal effect and therefore seems to be suitable as a local antiseptic agent but clinical studies need to be performed.

Keywords: Suprathel®, acetic acid, Acicoat®, Aquacel®, bacteria, burns