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42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie

02. - 04.06.2016, Augsburg

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Impact of preoperative thrombocytopenia on haemorrhagic risk and blood transfusion in patients undergoing radical cystectomy due to urothelial carcinoma

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  • T. Grimm - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • A. Buchner - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • B.-S. Schneevoigt - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • M. Apfelbeck - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • M.T. Grabbert - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • F. Jokisch - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • A. Kretschmer - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • G. Schulz - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • C.G. Stief - Ludwig-Maximilians-Universität München, Urologie, München, Germany
  • A. Karl - Ludwig-Maximilians-Universität München, Urologie, München, Germany

Bayerische Urologenvereinigung. Österreichische Gesellschaft für Urologie und Andrologie. 42. Gemeinsame Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie. Augsburg, 02.-04.06.2016. Düsseldorf: German Medical Science GMS Publishing House; 2016. DocKV23

doi: 10.3205/16urobay023, urn:nbn:de:0183-16urobay0231

Veröffentlicht: 20. April 2016

© 2016 Grimm et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

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Introduction and objectives: As recently shown perioperative blood transfusion is associated with impaired oncologic outcome in patients undergoing radical cystectomy (RC) for urothelial carcinoma (UC). In this study we analyzed the impact of preoperative thrombocytopenia (TP) on haemorrhagic risk and blood transfusion in patients undergoing RC due to UC.

Materials and methods: Data were available in 814 patients who underwent RC due to UC from 2004 to 2015 at one single german institution. Platelet count in these patients was gathered in our standardized preoperative setting one day before surgery. According to our boundary laboratory values TP was defined as < 150.000/µl. Chi²-test and Mann-Whitney-Test were used for analysis.

Results: Preoperative TP was detected in 4% (33/814) of our patients. Intraoperative blood loss, intraoperative and postoperative transfusion did not differ significantly in patients with or without preoperative TP. Intraoperative blood loss in those with and in those without preoperative TP was 700 ml (200-3500ml) and 600ml (50-8500ml) in median respectively (p=0.0373).

Intraoperative transfusion in those with and in those without preoperative TP was performed in 34% (11/32) and in 37% (282/770) of our patients respectively (p=0.769).

Further postoperative transfusion in patients with and without preoperative TP was required in 27% (9/33) and in 18% (138/770) of our patients respectively (p=0.769).

Conclusion: In our study preoperative TP has no significant impact on haemorrhagic rik and perioperative blood transfusion in patients undergoing RC due to UC. According to our data there's no instant need to treat preoperative TP in patients undergoing RC due to UC.