gms | German Medical Science

62. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

14. - 15.04.2016, Münster

Repair of vesico-vaginal fistula with amniotic membrane – Step 1 of IDEAL recommendations of surgical innovation

Meeting Abstract

  • presenting/speaker D. Barski - Lukas Krankenhaus Neuss, Urologie, Neuss, Germany
  • H. Gerullis - School of Medicine and Health Sciences, Carl von Ossietzky University, Oldenburg, University Hospital for Urology, Oldenburg, Germany
  • T. Ecke - Helios Klinikum Bad Saarow, Urologie, Bad Saarow, Germany
  • G. Varga - Universität Szeged, Experimentelle Chirurgie, Szeged, Hungary
  • M. Boros - Universität Szeged, Experimentelle Chirurgie, Szeged, Hungary
  • A. Winter - School of Medicine and Health Sciences, Carl von Ossietzky University, Oldenburg, University Hospital for Urology, Oldenburg, Germany
  • J.-W. Bagner - Lukas Krankenhaus Neuss, Urologie, Neuss, Germany
  • T. Otto - Lukas Krankenhaus Neuss, Urologie, Neuss, Germany

Nordrhein-Westfälische Gesellschaft für Urologie. 62. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie. Münster, 14.-15.04.2016. Düsseldorf: German Medical Science GMS Publishing House; 2016. DocP2.8

doi: 10.3205/16nrwgu75, urn:nbn:de:0183-16nrwgu750

Veröffentlicht: 25. Februar 2016

© 2016 Barski et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.


Gliederung

Text

Introduction: Amniotic membrane (AM) plays an increasing role as scaffold for the repair of defect tissue due to its unique biological properties which promote wound healing. AM is characterized by its durability and elasticity, it is antibacterial, non-antigenic and its stroma contains growth factors and cytokines.

Material and methods: We present a unique case of AM-assisted abdominal repair of a complex vesico-vaginal fistula (VVF) in a 64-year women after multiple abdominal surgery and radio-chemotherapy as Idea Stage following the IDEAL recommendations of surgical innovation. Homolog AM was harvested after cesarean section, cryopreserved, dried, prepared in three layers and was used as a graft to close the VVF-defect. Perioperative complications and functional results were obtained during the follow-up of 3, 6 and 12 mos.

Results: No severe complications, no graft rejection and no recurrent fistula were detected during the follow-up. The partial ingrowth of surrounding tissue on AM was found during cystoscopy.

Conclusion: For the first time we applied amniotic membrane graft assisted fistula repair. Following the IDEAL recommendations of surgical innovation preliminary case report showed the feasibility of the method. Further animal, cohort and randomised studies are needed to prove the procedure.