Artikel
Visualized identification of the maximal surgical delay effect in a rat flap model
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Autoren
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Xu Gong
- The first hospital of Ji Lin University, Chang Chun City, China
| Veröffentlicht: | 6. Februar 2020 |
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Gliederung
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Objectives/Interrogation: Currently, experimental evidence suggests that the surgical delay can increase flap survival area, but its effect may decrease if the optimal delay period is missed. The aim of this study is to establish a sensitive and objective modality based on the visualized and individualized infrared thermography for identifying the maximal surgical delay effect.
Methods: A rectangular three-angiosome flap was designed on the unilateral dorsum of the rat. Ninety-six rats were randomly divided into 6 groups according to the various delay time. Both the relative temperature and the relative temperature ratio were measured by the infrared thermography. Arterial density, number of vessels >0.1mm in diameter, microvessel density, VEGF concentration, and flap viability were measured. Receiving operating characteristic (ROC) curve with the highest Youden-Index was used to detect and identify an optimal cut-off point of the relative temperature ratio inratio in the maximal surgical delay effect.
Results and Conclusions: The criteria for identifying the flap maximum delay effect based on via the visualized and individualized the infrared thermaography l imaging were that included (1) the surface of the post-delayed flaps presented white color (higher temperature) instead of the red and white pattern of the normal the red area representing colder temperatures between the adjacent angiosomes was converted into the white area representing warmer temperature, and the surface of the post-delayed flaps formed a larger white area;skin and (2) the optimal cut-off point of the relative temperature ratio was more than 1.17 with a sensitivitya sensitivity of 84.6% and a specificity of 77.3%. Instead, the, the sensitivity and the specificity of the conventional method of based on the conventional delaydelay time for identifying the maximum delay effect were 38.5% and 90.9%, respectively.
Infrared thermal imaging can accurately identify the flap maximum delay effect when combined with the relative temperature ratio.
