gms | German Medical Science

Introduction: Fibro-osseous lesions (FOLs) of the maxillofacial region constitute a varied group of lesions characterized by replacement of normal bone by tissue composed of collagen and fibroblasts, with variable amounts of a mineralized substance that may be bone, cement or both. The objective of this study is to outline the differentiation, diagnosis and management of different types of FOLs of the maxillofacial region depending on retrospective basis in the previous four years.

Methods: A retrospective study of 10 patients admitted in the Otorhinolaryngology department, Faculty of Medicine, Cairo University, in the period between 2009 and 2012. All the patients were diagnosed as having FOLs of the maxillofacial region including fibrous dysplasia, cemento-ossifying fibroma, cherubism, giant cell tumor and Paget disease. Patients' age ranged from 10 to 52 years. They were 7 females and 3 males.

Results: The mean age was 25.4 years. The most frequent location was the maxilla (7 cases). There were 5 cases of fibrous dysplasia, 2 cases of cement-ossifying fibroma, 1 case of giant cell tumour, 1 case of cherubism and 1 case of Paget disease. Different surgical techniques were used in our study including: endoscopic excision: 3 cases, endoscopic debulking: 3 cases, Caldwell-Luc's operation: 1 case and partial maxillectomy: 1 case. Conservative management and follow up: 2 cases.

Conclusion: Radiology is central to the diagnosis of FOLs because the pathology for all of them is similar. Their treatment is highly individualized depending on the type of the lesion and its biological behavior, aggressiveness of the lesion and clinical presentation of the patient. Endoscopy plays an important role in the surgical management of FOLs.

Unterstützt durch: Otorhinolaryngology department, Faculty of Medicine, Cairo University.

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