gms | German Medical Science

In case of inflammatory process in paranasal sinus there is a risk of transfer infectional agents to orbital tissue. Different forms of orbital complications of acute purulent sinusitis take place in clinical practice (not often), but all of them are dangerous.

Objectives and Methods: The tasks of our work were to investigate the levels of intoxication in two groups of patients : one group with acute purulent sinusitis and palpebral oedema and the second group with acute purulent sinusitis only. We valued the level of intoxication with haematological index of intoxication (HI-index). This index was calculated using the data of blood analyse. The normal level of HI-index is from 0,3 to 1,5.

Results: In the first group all the patients had high significance of HI-index ( interval from minimal 2,1 to maximal 18,7; mostly from 4 to 8). It was the evidence of very severe toxic reaction, not only local, but common. There was a correlation between the number of paranasal sinuses with inflamation from one side and the level of HI-index to anothere. Significant part of the patients of the second group (62,2%) had normal HI-index. And 12,1% patients had HI-index less than 0,3. These patients demonstrated hyporeactive response to infection in the paranasal sinuses. For these patients not only anti-inflammatory, but immunostimulate therapy is necessary. In distinction from the first group, in the second group there was no correlation between the number of paranasal sinuses with inflamation and the level of HI-index.

Conclusions: Our data give the possibility to use HI- index for the value of intoxication in cases of acute purulent sinusitis with or without orbital complications. Besides, HI-index allows to coordinate drugs and surgical treatment for the best results.