Artikel
Long-term efficacy and side effects of upper airway stimulation – first results after 24 months of therapy
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Autoren
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Joachim T. Maurer
- University-ENT-Department, Mannheim, Germany
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Boris A. Stuck
- University-ENT-Department, Mannheim, Germany
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Clemens F. Anders
- University-ENT-Department, Mannheim, Germany
| Veröffentlicht: | 30. Juli 2013 |
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Gliederung
Text
Introduction: Respiration synchronised stimulation of the hypoglossal nerve during sleep offers a treatment option for patients with obstructive sleep apnea and CPAP non-adherence. So far there are no data regarding a 2 year treatment period.
Methods: 2010 and 2011 we implanted the Inspire® system in five patients with obstructive sleep apnea and CPAP-intolerance in a feasibility trial. Subjective and objective results were assessed by questionnaires and polysomnography.
Results: Two patients could not be investigated: One moved abroad, the other did not want to show up anymore as the feasibility study was officially terminated after 6 months. Three patients could be investigated. They used the stimulation therapy daily during the entire sleep period without sleep disturbances. Neither tongue movement impairment not hypertrophy could be detected. Stimulation intensity remained constant over time. There was no increased daytime sleepiness. AHI remained normal after 24 months (3.3, 7.0 and 6.5 respectively) versus baseline (33.3, 31.0 and 30.0 respectively).
Conclusion: Regular use of upper airway stimulation can be efficacious after 24 months bearing no relevant morbidity. Long-term follow-up is necessary in a larger cohort including a control group.
This study was supported by Inspire Medical, Minnesota, USA.
