Artikel
Orbital manifestation of Ormond’s disease
Suche in Medline nach
Autoren
Veröffentlicht: | 22. September 2005 |
---|
Gliederung
Text
Typically the Ormond’s disease appears as idiopathic retroperitoneal fibrosis. It is characterized by proliferation of fibrous tissue replacing the normal tissue in the central retroperitoneum. Usually the fibrosis involves the area between the renal arteries and sacrum, and causes encasement of the aorta, inferior vena cava and ureters, resulting in obstructive hydronephrosis.
We present a case of a 42-years-old female patient with a pronounced exophthalmus, ptosis, a reduced visual acuity and ophthalmoplegia of the right eye. Magnetic resonance (MR) images showed a soft tissue mass on contrast-enhanced T2-weighted images of the right orbita with inclusion of the muscles and the optical nerve. The lateral orbitotomy with biopsies, demonstrated fibrous tissue with infiltration of lymphocytes and plasma cells without any evidence of malignancy, confirming the diagnosis of Ormond’s disease. A retroperitoneal participation of the disease could be excluded.
Complaints were declining with a reduction of the exophthalmus, improved eye movement and an improved visual acuity. The further anti-inflammatory therapy was a combination of prednisolone and methotrexate.