gms | German Medical Science

Internationally there is growing concern about the robustness, reproducibility and transparency of biomedical research. Consequently there is a world wide quest to reduce waste and increase value in biomedical research. Since 2017, the QUEST (Quality-Ethics-Open-Science-Translation) Center at the Berlin Institute of Health aims at maximizing the quality, reproducibility, generalizability, and validity of Europe's largest university hospital and school (Charité) and a large biomedical research institute (Max Delbrück Center). To create an awareness of the need to rethink biomedical research and to initiate and sustain culture change in academic biomedicine, with a team of dedicated experts and specialists, QUEST is conducting large scale behavior change interventions [1] by fostering 1) capability (through education & services), 2) motivation (through incentives & education), and 3) opportunity (through services) to increase research value. In my introductory talk I will present the principles and processes underpinning the rationale for all QUEST activities, some of which will be elaborated in greater detail by the following speakers.

The authors declare that they have no competing interests.

The authors declare that an ethics committee vote is not required.