Artikel
Multifocal electroretinography and OCT in segmental retinitis pigmentosa
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Autoren
Veröffentlicht: | 22. September 2004 |
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Gliederung
Text
Objective
Generalized retinal degenerations such as retinitis pigmentosa (RP) may manifest with focal retinal dysfunctions. These may be detected objectively by new electrophysical techniques, such as multifocal electroretinography or by OCT images.
Case report
A 33 years old female patient, showed bilateral caudal bone spiculae formations with corresponding cranial field defects in the static perimetry of the central visual field (Octopus) and in the kinetic perimetry (Goldmann).
Results
Cone ERG were within the normal range. The multifocal cone ERG of the central 50° showed reduced amplitudes and prolonged latencies in the first-order response component. These findings corresponded to the area of the bone spiculae and scotoma. OCT images showed the displacement of pigmented retinal pigment epithelial (RPE) cells, which forward in to the inner layers of the neural retina. The retinal thickness was decreased in the areas of the retina affected by RP, and nearly normal in the unaffected area.
Conclusions
Multifocal ERG and OCT enables the detection of focal retinal cone dysfunction in segmental retinitis pigmentosa. these additional tools may aid in the diagnosis and classification of this disease.