gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

Screening for retinopathy of prematurity (ROP): results from one centre between 1991 - 2002

Meeting Abstract

  • corresponding author C. Jandeck - Augenklinik, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin
  • U. Kellner - RetinaScience, Bonn
  • H. Heimann - Augenklinik, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin
  • M.H. Foerster - Augenklinik, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogFR.06.08

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog212.shtml

Veröffentlicht: 22. September 2004

© 2004 Jandeck et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.


Gliederung

Text

Objective

To analyse the results of ROP screening, stage of disease and time of treatment from a university hospital. Review of the German screening criteria.

Methods

Between 1991 und 2001, 666 infants with a gestational age (GA) <33 weeks or birth weight (BW) less than <1501g, and 22 children with multiple diseases and a GA 33-35 of weeks were examined. Coagulation treatment was performed in accordance with the Cryo-ROP study, after reaching the threshold. All infants were followed-up until a stable retinal situation was reached.

Results

Mean GA of the 666 infants was 28.5±2.3 weeks. Mean BW was 1180±372 g. During the years of screening, the GA and BW significantly decreased, but no significant change in the yearly incidence of ROP was detected. 460 (69.1%) of the infants did not develop any stage of ROP. Maximum stage of ROP in the worse eye was stage one in 51 (7.6%) infants, stage two in 59 (8.9%) infants and stage three below threshold in 62 (9.3%) infants. 34 (5.1%) infants were treated with coagulation treatment. Mean time of treatment was 36.5 weeks postmenstrual age, or 10.7 weeks postnatal age. Postnatal age showed a better correlation to treatment time than postmenstrual age. No infant was treated before seven weeks of life and not before 32 weeks postmenstrual age. Of the 22 children who could be classed as very sick only 2 developed ROP (stage 2 / stage 3).

Conclusions

Despite increasing survival of children with lower GA and BW the incidence of ROP did not show since of increasing, and the incidence of ROP in our centre appears to be comparable to other international studies. In contrast to the Cryo-ROP study, treatment time correlates better to postnatal age than to postmenstrual age. With German screening criteria, all infants who underwent treatment were detected at an appropriate time and no infant went undetected.