gms | German Medical Science

102. Jahrestagung der DOG

Deutsche Ophthalmologische Gesellschaft e. V.

23. bis 26.09.2004, Berlin

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Effect of IOLs with different surface structure on lens epithelial cells (LEC) in vitro on human capsular bag model

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  • corresponding author N. Torun - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • N. Pahms - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • A. Porstmann - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • C. Hartmann - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum
  • A. Liekfeld - Charité, Clinic of Ophthalmology, University School of Medicine Berlin, Campus Virchow Klinikum

Evidenzbasierte Medizin - Anspruch und Wirklichkeit. 102. Jahrestagung der Deutschen Ophthalmologischen Gesellschaft. Berlin, 23.-26.09.2004. Düsseldorf, Köln: German Medical Science; 2004. Doc04dogDO.05.06

Die elektronische Version dieses Artikels ist vollständig und ist verfügbar unter: http://www.egms.de/de/meetings/dog2004/04dog047.shtml

Veröffentlicht: 22. September 2004

© 2004 Torun et al.
Dieser Artikel ist ein Open Access-Artikel und steht unter den Creative Commons Lizenzbedingungen (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.de). Er darf vervielfältigt, verbreitet und öffentlich zugänglich gemacht werden, vorausgesetzt dass Autor und Quelle genannt werden.

Gliederung

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Objective

To investigate the effect of intraocular lenses (IOL) with different surface structure on lens epithelial cells (LEC) in vitro on human capsular bags.

Methods

Sham cataract surgery, including IOL-into-the-bag-implantation, was performed on 8 pair of donor eyes after removal of the cornea. The capsular bag including the IOL was removed, pinned on a culture dish, covered with medium, and incubated. In each pair of donor eyes, the two different Silicone-IOLs to be compared, were implanted individually into capsular bags. One eye was assigned to receive a IOL with Fresnel rim structure (Acrisil-73N AL) and the other eye, an IOL without a Fresnel rim structure (Acrisil-73N OM). The time required for complete coverage of the posterior capsule by a confluent monolayer of LEC was documented.

Results

Complete LEC coverage of the posterior capsule occurred between 9 days (Acrisil-73N AL) and after more than 19 days (Acrisil-73N OM). Mean time for total LEC coverage on the posterior capsule was 14.25 (+2.8) days in the capsular bag group with the Acrisil-73N AL implanted. For the Acrisil-73N OM group it was 11.5 (+1.5) days.

Conclusions

The Acrisil-73N AL was associated with a later complete cell coverage of the posterior capsule than the Acrisil-73N OM.