gms | German Medical Science

Purpose: To report a 26-year-old male with bilateral Eales’ disease which led to total blindness in the left eye and legal blindness in the right eye in a short time.

Methods: In that case were performed a total clinical systemic examination, computed tomography, magnetic resonance imaging, genetic testing, and optical coherence tomography.

Results: The eye condition was managed by scatter laser treatment, Anti-VEGF injections, anterior chamber paracentesis and trabeculectomy. Non-steroidal eye drops as well as prostaglandin analogues, beta-blockers, and carbonic anhydrase inhibitors have been used as local treatment. Systemic treatment included an intravenous methylprednisolone course, oral corticosteroids, azathioprine, mycophenolate mofetil and total amount of 12 Anti-VEGF injections.

Conclusion: Despite aggressive treatment with oral steroids, immunosuppressants, anti-VEGF injections, there were many exacerbations, and remission was not achieved. As a result, aggressive neovascular glaucoma developed, which led to total blindness in the left eye and legal blindness in the right eye.