gms | German Medical Science

Purpose: To illustrate the effectiveness of our BC (bag and chamber) flushing technique through experiments and clinical application. This technique was developed with the aim of reducing the rate of postoperative endophthalmitis to zero.

Methods: In our series of experiments to evaluate the potential of flushing over aspiration, we simulated I/A using a pig’s eye injected with an Ophthalmic Visco-elastic Device (OVD) and coffee creamer. We also devised experiments using an electric fan, a vacuum cleaner and an air spray gun. In our clinical trial, we applied diluted Moxifloxacin (MFLX) at various concentrations intracamerally in around 14,000 patients.

Results: In our pig’s eye simulation using an OVD mixed with a coffee creamer, we proved that tapping was not so effective for residual substances behind the IOL. In the series of experiments using the fan, vacuum cleaner and air spray gun, we could also prove our theory that flushing is more powerful than aspiration. In order to remove residual substances behind the IOL and in the capsular bag, flushing proved more effective than aspiration. In our clinical trial, “BC Flushing” with 500 µg/ml of diluted MFLX was the most effective formulation. The rate of endophthalmitis was 0.00% in around 14,000 cases.

Conclusions: Full bag and chamber flushing is more effective than aspiration. We believe that “BC Flushing” is a simple, easy, effective and innovative method against postoperative endophthalmitis.