gms | German Medical Science

19. Deutscher Kongress für Versorgungsforschung

Deutsches Netzwerk Versorgungsforschung e. V.

30.09. - 01.10.2020, digital

Activity matters: the German adaptation and pilot evaluation of a web-based self-management program to improve physical activity levels among people with multiple sclerosis

Meeting Abstract

  • Karin Riemann-Lorenz - Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland
  • Nicole Krause - Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland
  • Blathin Casey - Physical Activity for Health Cluster, Health Research Institute, University of Limerick, Irland
  • Christoph Heesen - Institut für Neuroimmunologie und Multiple Sklerose, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland

19. Deutscher Kongress für Versorgungsforschung (DKVF). sine loco [digital], 30.09.-01.10.2020. Düsseldorf: German Medical Science GMS Publishing House; 2020. Doc20dkvf173

doi: 10.3205/20dkvf173, urn:nbn:de:0183-20dkvf1731

Veröffentlicht: 25. September 2020

© 2020 Riemann-Lorenz et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe



Background: Regular physical activity (PA) and exercise can improve the symptoms of multiple sclerosis (MS) [1], [2], reduce the number of relapses, and at the same time reduce the risk of comorbidities, which in turn negatively affect MS disease course [3]. Despite this, people with MS report low rates of PA [4]. ‘Activity Matters’ is a web-based self-management program from Ireland that aims to change PA behavior and improve PA levels among people with MS. The resource was systematically developed using a theory-based approach and includes a variety of behavior change techniques [5].

Objectives: The aims of the study are to translate and adapt ‘Activity Matters’ to the German context. Acceptance and use of the program by people with MS from the Metropolitan Area of Hamburg will be evaluated as well as the effect on levels of physical activity and quality of life.

Methods and hypothesis: The website content was professionally translated to German. Existing video material was analyzed and replaced by newly shot videos with German experts and patients. We updated scientific references included in the program and added German abstracts that are understandable to laypeople. The website content was culturally adapted where necessary. Local sports options for people with MS with different disability levels have been included. A feasibility study with 5-10 people with MS and MS experts will check for accessibility, comprehensibility, acceptance and appropriateness. Informed by the results of the feasibility study, a pilot study with n=50 participants will evaluate usability, acceptability and adherence to the 12-week intervention. Results of the pilot study will inform the design of a pilot RCT. We hypothesize, that using the web-based self-management program ‘Activity Matters’ will lead to increased physical activity and improved quality of life.

Results: The results of the adaptation process and feasibility study as well as the design for the pilot study will be presented.

Implications for practice: Web-based self-management programs might improve healthcare and lead to a more active lifestyle among people with MS.


Latimer-Cheung AE, Pilutti LA, Hicks AL, Martin Ginis KA, Fenuta AM, MacKibbon KA, Motl RW. Effects of exercise training on fitness, mobility, fatigue, and health-related quality of life among adults with multiple sclerosis: a systematic review to inform guideline development. Arch Phys Med Rehabil. 2013 Sep;94(9):1800-1828.e3. DOI: 10.1016/j.apmr.2013.04.020 Externer Link
Heine M, van de Port I, Rietberg MB, van Wegen EE, Kwakkel G. Exercise therapy for fatigue in multiple sclerosis. Cochrane Database Syst Rev. 2015 Sep;(9):CD009956. DOI: 10.1002/14651858.CD009956.pub2 Externer Link
Marrie RA, Rudick R, Horwitz R, Cutter G, Tyry T, Campagnolo D, Vollmer T. Vascular comorbidity is associated with more rapid disability progression in multiple sclerosis. Neurology. 2010 Mar;74(13):1041-7. DOI: 10.1212/WNL.0b013e3181d6b125 Externer Link
Casey B, Coote S, Galvin R, Donnelly A. Objective physical activity levels in people with multiple sclerosis: Meta-analysis. Scand J Med Sci Sports. 2018 Sep;28(9):1960-1969. DOI: 10.1111/sms.13214 Externer Link
Casey B, Coote S, Byrne M. Activity matters: a web-based resource to enable people with multiple sclerosis to become more active. Transl Behav Med. 2019 Jan;9(1):120-128. DOI: 10.1093/tbm/iby028 Externer Link