gms | German Medical Science

Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2019)

22. - 25.10.2019, Berlin

The dynamic changes of perioperative deep vein thrombosis in lower extremity fracture patients: an observational study

Meeting Abstract

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  • presenting/speaker Bin-Fei Zhang - Honghui Hospital, Xi'an Jiaotong University, Xi'an, China
  • Peng-Fei Wang - Honghui Hospital, Xi'an Jiaotong University, Xi'an, China
  • Yan Zhuang - Honghui Hospital, Xi'an Jiaotong University, Xi'an, China

Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2019). Berlin, 22.-25.10.2019. Düsseldorf: German Medical Science GMS Publishing House; 2019. DocIN46-965

doi: 10.3205/19dkou730, urn:nbn:de:0183-19dkou7307

Veröffentlicht: 22. Oktober 2019

© 2019 Zhang et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.


Gliederung

Text

Objectives: For patients with lower extremity fractures, perioperative deep venous thrombosis (DVT) prevention is needed to prevent fatal pulmonary embolism. However, the dynamic change of DVT during this stage is unclear in patients receiving anticoagulation treatment. This study aimed to investigate the dynamic changes of DVT in patients with lower extremity fractures receiving anticoagulation treatment in perioperative stage.

Methods: We collected the clinical data of 404 patients with lower extremities fractures who presented at Xi'an Honghui Hospital between June 1, 2016 to March 31, 2017 and met all the inclusion criteria. Doppler ultrasonography was used to diagnose DVT. The patients were examined at preoperation, postoperation and 1 month after operation. The patients were divided into a thrombosis group and a non-thrombosis group according to the ultrasonographic findings.

Results and conclusion: The incidence of preoperative DVT was 35.39%, the prevalence of DVT on the uninjured side was 12.17%, multivariate analysis showed age (odds ratio [OR], 1.03; 95% CI, 1.01-1.04; P = 0.000) was independent risk factors of preoperative DVT. The incidence of postoperative DVT was 55.20%, the prevalence of DVT on the uninjured side was 21.69%, multivariate analysis showed that age (OR, 1.04; 95% CI, 1.03-1.05; P = 0.000), blood loss (OR, 1.001; 95% CI, 1.000-1.002; P = 0.018) and American Society of Anesthesiologists (ASA) classification (OR, 2.07; 95% CI, 1.16-3.72; P = 0.014) were independent risk factors for postoperative DVT. The incidence of postoperative 1 month DVT was 39.85%, the prevalence of DVT on the uninjured side was 19.58%, the results of multivariate analysis showed that age (OR, 1.05; 95% CI, 1.03-1.07; P = 0.000) was independent risk factors for postoperative 1month DVT.In conclusion, the incidences of perioperative DVTs did not decrease as time goes on in patients receiving anticoagulation treatment. Age was an important risk factor for perioperative DVT.