gms | German Medical Science

44. Kongress der Deutschen Gesellschaft für Rheumatologie, 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie, 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie

31.08. - 03.09.2016, Frankfurt am Main

Proof of concept – study for the evaluation of healthy joints and periarticular structures in children

Meeting Abstract

  • Nikolay Tzaribachev - Pediatric Rheumatology Research Institute, Kinderrheumatologie, Bad Bramstedt
  • Marlene Naumann - Charité, Berlin, Med. Klinik mit SP Rheumatologie und Klin. Immunologie, Berlin
  • Ghada El Mardenly - University of Cairo, Rheumatology, Cairo
  • Marina Backhaus - Park-Klinik Weissensee, Abteilung für Innere Medizin - Rheumatologie und Klinische Immunologie, Berlin
  • Sarah Ohrndorf - Charité - Universitätsmedizin Berlin, Medizinische Klinik mit Schwerpunkt Rheumatologie und klinische Immunologie, Berlin

Deutsche Gesellschaft für Rheumatologie. Deutsche Gesellschaft für Orthopädische Rheumatologie. Gesellschaft für Kinder- und Jugendrheumatologie. 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR). Frankfurt am Main, 31.08.-03.09.2016. Düsseldorf: German Medical Science GMS Publishing House; 2016. DocDI.12

doi: 10.3205/16dgrh155, urn:nbn:de:0183-16dgrh1557

Veröffentlicht: 29. August 2016

© 2016 Tzaribachev et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.


Gliederung

Text

Background: Musculoskeletal ultrasonography (MSUS) has become an important diagnostic tool for the diagnosis and follow-up of inflammatory joint diseases in children, especially in juvenile idiopathic arthritis (JIA). However, only few studies on a small number of patients are available so far, producing an immanent need for further knowledge on the ultrasonographic appearance of periarticular and joint structures in healthy children. This is especially true for the presence of Power Doppler activity in healthy joints.

The aim of the study was to evaluate normal values for the thickness of healthy joint cartilage, capsule and tendons of the hand (finger/wrist), elbow, hip, knee, ankle and forefoot in children by musculoskeletal ultrasound (US). More over, the question about the presence of Power Doppler activity in healthy joints was addressed.

Methods: Four MSUS experienced OMERACT MSUS SIG sonographers used 4 equally preset Esaote Mylab Twice machines, 13-18 MHz probes, to examine N=75 healthy children (34 girls), 4.3-13.1 years old, who have successfully passed a detailed health questionnaire assuring the lack of underlying pathology.

Statistics: for the standard reference intervals normal or lognormal distributions were assessed and calculated with Shapiro-Wilk W Test / Kolmogorov's D test.

Results: In most joints a relatively wide range of the measurements of periarticular and joint structures was found with a geometrical mean between 0.54 and 4.59. In younger children the range was even wider. PDUS signals were commonly detectable in all joints, predominantly in wrist, finger and knee joints.

Conclusion: The reference intervals for healthy children are needed for the interpretation of pathological findings in JIA. Due to the wide range in both grey scale and PDUS, pathology should be examined carefully in terms of under-/overinterpretation. Especially in younger children, joint measurements might have different values due to the growing structures, which need further evaluation.