gms | German Medical Science

73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

29.05. - 01.06.2022, Köln

Artikel

Artikel empfehlen

Examination of the somatosensory profile using quantitative sensory testing (QST) during dorsal root ganglion stimulation for unilateral chronic neuropathic pain

Untersuchung des somatosensorischen Profils mittels quantitativer sensorischer Testung (QST) während der Spinalganglionstimulation bei einseitigen chronischen neuropathischen Schmerzen

Meeting Abstract

Suche in Medline nach

  • presenting/speaker Matthias Morgalla - Universitätsklinikum Tübingen, Klinik für Neurochirurgie, Tübingen, Deutschland
  • Valerie Martin - Universitätsklinikum Tübingen, Klinik für Neurochirurgie, Tübingen, Deutschland
  • Marcos Tatagiba - Universitätsklinikum Tübingen, Klinik für Neurochirurgie, Tübingen, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie. Köln, 29.05.-01.06.2022. Düsseldorf: German Medical Science GMS Publishing House; 2022. DocP211

doi: 10.3205/22dgnc527, urn:nbn:de:0183-22dgnc5275

Veröffentlicht: 25. Mai 2022

© 2022 Morgalla et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: Due to nerve damage, neuropathic pain often affects also other sensory nerve fibre qualities. The aim of our study was to investigate the effects and possible differences of dorsal root ganglion stimulation (DRGS) on the somatosensory profiles of patients with chronic neuropathic pain of one limb using quantitative sensory testing (QST).

Methods: From March 2017 until October 2020 we have examined 15 patients (6 women, 9 men; mean age 56 years) with chronic unilateral neuropathic pain (11 groins, 2 knees, 2 feet), who have been treated with DRGS. We used QST (7 tests, 13 parameters). The stimulation was switched off for 4 hours (washout) and afterwards a basic measurement was performed on the control side and the painful side (randomized). Then, the stimulation was switched on and after 45 min the measurement was repeated on the control side and painful side (randomized). The results of the painful side were compared to the control side.

Results: A comparison of the painful area and the control area in the patients shows significant differences in heat and cold detection: WDT (p in OFF <0.001, p in ON = 0.006) and CDT, (p in OFF = 0.001, p in ON = 0.006), for heat pain (HPT (p in ON = 0.040), the thermal sensory limen (TSL (p in OFF = 0.010, p in ON <0.001), the mechanical detection and pain threshold (MDT ( p in OFF = 0.006, p in ON = 0.011) and MPT (p in ON = 0.066) and the vibration threshold (VDT (p in OFF <0.001, p in ON <0.001).

Conclusion: This is the first study using QST and examining the possible changes of sensory qualities under DRGS. DRGS also seems to be able to influence the sensory qualities of fibres which have been altered in chronic pain patients. Further studies are necessary in order to clarify the underlying mechanisms.