gms | German Medical Science

73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

29.05. - 01.06.2022, Köln

Intracranial lesion patterns and their association with full recovery in adolescents and young people with mild traumatic brain injury

Intrakranielle Läsionsmuster und ihr Zusammenhang mit der funktionellen Erholung bei Jugendlichen und jungen Menschen mit leichtem Schädel-Hirn-Trauma

Meeting Abstract

  • presenting/speaker Alexander Younsi - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Lennart Riemann - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Ana Mikolic - Erasmus MC University Medical Center Rotterdam, Department of Public Health, Rotterdam, Niederlande
  • Andrew Maas - Antwerp University Hospital, Department of Neurosurgery, Antwerp, Belgien
  • Klaus Zweckberger - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland
  • Andreas W. Unterberg - Universitätsklinikum Heidelberg, Neurochirurgische Klinik, Heidelberg, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie. Köln, 29.05.-01.06.2022. Düsseldorf: German Medical Science GMS Publishing House; 2022. DocV064

doi: 10.3205/22dgnc069, urn:nbn:de:0183-22dgnc0693

Veröffentlicht: 25. Mai 2022

© 2022 Younsi et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.


Gliederung

Text

Objective: Mild traumatic brain injury (mTBI) is a very common injury in young people. It can be accompanied by structural damage to the brain which is typically detected using CT imaging. Here, we investigated how CT abnormalities and patterns relate to the long-term global functional outcome in young patients with mTBI.

Methods: All patients with mTBI (GCS 13-15) ≤24 years in the multi-center, prospectively collected, observational CENTER-TBI study were included. Patient demographics, CT findings, and GOSE scores at 12 months follow-up were retrieved. Demographical, clinical, and radiographic characteristics were analyzed. The association between CT abnormalities and functional recovery was assessed using multivariable mixed ordinal and logistic regression models.

Results: A total of 462 eligible patients with mTBI and initial brain CT from 46 study centers in Europe were included. The median age was 19 (17-22) years, and 322 (70%) were males. CT imaging showed an intracranial pathology in 171 patients (37%), most commonly subarachnoid hemorrhages, followed by contusions, and epidural hematomas. Patients with a positive CT scan were less likely to achieve a complete recovery 12 months postinjury than patients with a negative CT scan (54% vs. 77%). The presence of any CT abnormality was associated with both lower GOSE scores and incomplete recovery (GOSE <8) at 12 months follow-up, also when adjusted for demographical and clinical baseline factors.

Conclusion: In this study of young patients with mTBI, the presence of CT abnormalities was predictive of global outcome 12 months after brain injury. This might help to identify patients at risk for an incomplete recovery who might benefit from early follow-up and additional care.