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73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

29.05. - 01.06.2022, Köln

Radiosurgery for parasagittal meningiomas

Radiochirurgie bei parasagittalen Meningiomen

Meeting Abstract

  • presenting/speaker Antonio Santacroce - St. Barbara-Klinik Hamm-Hessen, Neurochirurgie, Hamm, Deutschland
  • Makoto Nakamura - Krankenhaus Köln-Merheim, Klinikum der Universität Witten/Herdecke, Klinik für Neurochirurgie, Köln, Deutschland
  • Jean Regis - CHU La Timone, Neurosurgery, Marseille, Frankreich
  • Thomas Fortmann - St. Barbara-Klinik Hamm-Hessen, Neurochirurgie, Hamm, Deutschland
  • Christian Ewelt - St. Barbara-Klinik Hamm-Hessen, Neurochirurgie, Hamm, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie. Köln, 29.05.-01.06.2022. Düsseldorf: German Medical Science GMS Publishing House; 2022. DocV041

doi: 10.3205/22dgnc049, urn:nbn:de:0183-22dgnc0493

Veröffentlicht: 25. Mai 2022

© 2022 Santacroce et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.


Gliederung

Text

Objective: Parasagittal meningiomas are benign tumors which are dreaded for their surgically hardly accessible location with respect to infiltration of superior sagittal sinus. Treatment options of most of benign parasagittal meningiomas are radical microsurgery, debulking followed by radiosurgery or radiosurgery as first treatment option.

We report on the efficacy of Gamma Knife radiosurgery (GKRS) for the treatment of parasagittal meningiomas, comparing these major skull base subgroups with respect to infiltration of the sagittal sinus

Methods: From 15 participating centers under the auspices of the european Gamma Knife Society, we performed a retrospective observational analysis of a cohort of 237 benign meningiomas treated with GKRS.

All were treated with Gamma Knife radiosurgery at least 5 years before assessment for this study. Clinical and imaging data were retrieved from each center and uniformly entered into a database by 1 author (A.S.). A comparative analysis is presented.

Results: 192 patients harboring 237 meningiomas treated in fifteen institutions recruited were evaluated. 157 were parasagittal meningiomas without sinus infiltration 80 showed no sinus infiltration. The median age was 58 years old. The median tumour volume was 4.00 cc. The median tumour margin dose to the 50 % isodose line was 14.2 Gy. The median cumulative imaging follow-up was 60 months. The detailed results from 210 meningiomas (88%) were available for analysis. The actuarial control rate was 92% at 5 years post GKRS. The permanent morbidity rate was 8.1%.

A main limitation is the retrospective nature of data retrieval.

Conclusion: Radiosurgery is a safe and not invasive method of treatment of parasagittal meningiomas and the large number analyzed shows a high imaging tumor control and low morbidity rate even in the medium to long-term.

Different control rates are observed for those tumors showing sinus infiltration.