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72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

06.06. - 09.06.2021

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Multiple intracranial aneurysms – the PHASES Scores applicability and accuracy in 275 patients harbouring 661 intracranial aneurysms

Multiple intrakranielle Aneurysmen – die Anwendung und Genauigkeit des PHASES Scores bei 275 Patienten mit insgesamt 661 intrakraniellen Aneurysmen

Meeting Abstract

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  • Belal Neyazi - Otto-von-Guericke University Magdeburg, Department of Neurosurgery, Magdeburg, Deutschland
  • presenting/speaker Vanessa M. Swiatek - Otto-von-Guericke University Magdeburg, Department of Neurosurgery, Magdeburg, Deutschland
  • Amir Amini - Otto-von-Guericke University Magdeburg, Department of Neurosurgery, Magdeburg, Deutschland
  • Celina E. Sandalcioglu Ortuño - Otto-von-Guericke University Magdeburg, Department of Neurosurgery, Magdeburg, Deutschland
  • Sylvia Saalfeld - Otto-von-Guericke University Magdeburg, Department of Simulation and Graphics, Magdeburg, Deutschland; Research Campus STIMULATE, Magdeburg, Deutschland
  • Jörg Hattingen - KRH Klinikum Nordstadt, Institut für Radiologie, Hannover, Deutschland
  • Martin Skalej - Otto-von-Guericke University Magdeburg, Magdeburg, Deutschland
  • Klaus-Peter Stein - Otto-von-Guericke University Magdeburg, Department of Neurosurgery, Magdeburg, Deutschland
  • I. Erol Sandalcioglu - Otto-von-Guericke University Magdeburg, Department of Neurosurgery, Magdeburg, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie. sine loco [digital], 06.-09.06.2021. Düsseldorf: German Medical Science GMS Publishing House; 2021. DocP190

doi: 10.3205/21dgnc471, urn:nbn:de:0183-21dgnc4712

Veröffentlicht: 4. Juni 2021

© 2021 Neyazi et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: The subgroup of patients with multiple intracranial aneurysms (MIA) accounts for about 20% of all patients suffering from intracranial aneurysms (IA). There are controversial findings regarding a higher rupture risk in patients with MIA, leading to uncertainties in assessment of individual risk for aneurysm rupture. We performed a subgroup - evaluation of the PHASES Score with respect to its applicability on patients with MIA.

Methods: We analyzed 275 patients harboring a total number of 661 MIA regarding the accuracy of the PHASES Score for prediction of SAH using Receiver Operating Characteristics (ROC). Additionally, we analyzed the patients with aneurysmal subarachnoid hemorrhage (SAH) more closely.

Results: The PHASES Score achieved an area under the curve (AUC) of 0.57 in prediction of SAH in patients with MIA with corresponding sensitivity of 60% and specificity of 46%. We observed the following distribution of corresponding 5-year rupture risk in patients with aneurysmal SAH: <1% risk (40%), 1-1.9% risk (30%), 2-4.9% risk (19%) and >5% risk (11%).

Conclusion: The PHASES Score shows low sensitivity and specificity in prediction of aneurysm rupture in patients with MIA. Patients harboring MIA and suffering from a SAH seem to be categorized as patients with singular IA. The use of new specific analytical tool to predict the rupture risk in patients with MIA is mandatory.