Artikel
Vario-guided biopsy vs. stereotactic frame biopsy – a single-centre experience
Vario-gesteuerte Biopsie vs. stereotaktische Rahmenbiopsie – eine Single-Center-Experience
Suche in Medline nach
Autoren
Veröffentlicht: | 4. Juni 2021 |
---|
Gliederung
Text
Objective: Stereotactic needle biopsy is a common procedure in neurosurgery for deep-seated or multiple brain lesions. The objective of this study was to compare skin-to-skin, duration of anesthesia, negative biopsy rates an number of complications in a frame-based vs. a frameless setup.
Methods: We analyzed all frame based (i.e. Leksell Stereotactic System) and frameless (i.e. Vario-guided) biopsies performed at the Department of Neurosurgery in the University-Hospital of Bonn during 01/18 and 08/2020. Assessment of operative times used the local operating room database whereas radiology database and histological results were used to evaluate bleeding complications and negative biopsy rates. After testing values for Gaussian distribution using Shapiro-Wikl normality tests, we tested for significance using Mann-Whitney testing.
Results: In total 109 biopsies (i.e. 40 vario-guided vs. 69 frame guides biopsies) were compared. Vario-guided biopsies showed significantly shorter duration of anesthesia (163 min median with IQR 138-194 min vs. 193 min median with IQR 167 – 215 min; p= 0.0009). We saw no difference in skin to skin time (28 min median with IQR 20-38 vs 30 min median with IQR 25-39; p= 0.1352) and no difference in complications such as bleeding or infection (2 of 40 vs. 4 of 69; p=0.7133). We found a slight higher false-negative biopsy rate in frameless than in frame guided biopsies (3 vs 1; p= 0.1347).
Conclusion: Vario guided biopsies showed significant shorter time under anesthesia and did not show any difference in complication rate compared to frame guided biopsy. Frameless biopsy could therefore be used as an time-saving alternative patients with large cerebral lesions.