Artikel
Health-related quality of life after microscopically total removal of spinal intramedullary ependymomas with safe and precise strategy in a single-institute 3-year prospective study
Gesundheitsbezogene Lebensqualität nach mikroskopischer Totalentfernung von spinalen intramedullären Ependymomen mit sicherer und präziser Strategie in einer 3-jährigen prospektiven Studie mit einem einzigen Institut
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Autoren
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Yuta Nakanishi
- Osaka City University, Department of Neurosurgery, Osaka, Japan
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Kentaro Naito
- Osaka City University, Department of Neurosurgery, Osaka, Japan
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Toru Yamagata
- Osaka City General Hospital, Department of Neurosurgery, Osaka, Japan
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Kenji Ohata
- Osaka City University, Department of Neurosurgery, Osaka, Japan
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Toshihiro Takami
- Osaka City University, Department of Neurosurgery, Osaka, Japan
| Veröffentlicht: | 26. Juni 2020 |
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Gliederung
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Objective: A single-institute, 3-year, prospective study was conducted to examine HRQOL after microscopically total removal of spinal intramedullary ependymomas with a safe and precise strategy.
Methods: A cohort of 20 patients with a possible diagnosis of spinal intramedullary benign ependymomas was recruited. This study included those patients who underwent microscopically total removal of the tumor and for whom the pathological diagnosis was verified as benign ependymoma of World Health Organization grade 2. A final total of 16 patients (average age 48.7 years) was eligible for study analysis. Careful assessment was performed for all patients before and 6–12 months after surgery. The short-form 36 Health Survey (SF-36) was used to assess HRQOL, with the surveyor recording answers as reported by the individual patient.
Results: Functional outcomes appeared satisfactory or acceptable with minimal surgery-related complications. Average total HRQOL score was 431.1 before surgery and was maintained at 434.2 at 6–12 months postoperatively. Patients with mild functional symptoms preoperatively tended to demonstrate a higher total HRQOL score preoperatively compared with patients showing moderate to severe functional symptoms preoperatively. A strong correlation was noted between postoperative functional conditions and preservation of HRQOL.
Conclusion: Microscopically total removal of spinal intramedullary ependymoma under a safe and precise strategy appears justifiable in preventing progressive aggravation of HRQOL.
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