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70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

12.05. - 15.05.2019, Würzburg

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Thalamic deep brain stimulation for dystonic head tremor

Thalamische tiefe Hirnstimulation bei dystonem Kopftremor

Meeting Abstract

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  • presenting/speaker Assel Saryyeva - Medizinische Hochschule Hannover, Neurochirurgie, Hannover, Deutschland
  • Marc Wolf - Universitätsmedizin Mannheim, Neurologie, Mannheim, Deutschland
  • Christian Blahak - Ortenau Lahr Ettenheim, Neurologie, Lahr, Deutschland
  • Joachim Runge - Medizinische Hochschule Hannover, Neurochirurgie, Hannover, Deutschland
  • Joachim K. Krauss - Medizinische Hochschule Hannover, Neurochirurgie, Hannover, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie. Würzburg, 12.-15.05.2019. Düsseldorf: German Medical Science GMS Publishing House; 2019. DocV089

doi: 10.3205/19dgnc104, urn:nbn:de:0183-19dgnc1049

Veröffentlicht: 8. Mai 2019

© 2019 Saryyeva et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: We aimed to evaluate the clinical benefit of Vim DBS in patients with dystonic head tremor.

Methods: Patients with dystonic head tremor were scheduled for Vim DBS. All patients were clinically characterized according to the Burke-Fahn-Marsden (BFM) motor and disabilityrating scale (BFM-M/BFM-D) and the modified Fahn-Tolosa-Marin Tremor Rating Scale (mFTMTRS) (0–12 point scale for head tremor) pre- and postoperatively. Statistical analysis for significant pre- and postoperative changes in BFM-M/BFM-D and mFTMTRS was performed using the Wilcoxon Rank test for paired variables.

Results: 15 consecutive patients with dystonic head tremor underwent Vim DBS (6 male, mean age at DBS 49.7+/-11.8 years). Mean follow-up (FU) duration was 41 months (median 17 months). The mean preoperative BFM-M was 21.8+/-11.5, which improved to 12.2+/-10.5 at last FU (-44.5%, p<0.05), and the mean preoperative BFM-D was 5.1+/-2.9, which improved to 3.4+/-4.1 at last FU (-33.3%, p<0.05), while the mean preoperative mFTMTRS was 8.7+/-2.5, which improved to 3.5+/-2.7 at last FU (-59.8%, p<0.005).

Conclusion: Thalamic DBS should be considered as a primary therapeutic option in patients with segmental dystonia with prominent tremor. Indeed, patients experienced a significant relief of their tremor but also other dystonic symptoms improved significantly as reflected by the BFM.