Artikel
Quality of life analysis in patients treated for aneurysm rupture
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Autoren
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Evgenia Divizieva
- Heinrich-Heine-Universität, Universitätsklinikum, Klinik für Neurochirurgie, Düsseldorf, Deutschland
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Jan Frederick Cornelius
- Heinrich-Heine-Universität, Universitätsklinikum, Klinik für Neurochirurgie, Düsseldorf, Deutschland
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Igor Fischer
- Heinrich-Heine-Universität, Universitätsklinikum, Klinik für Neurochirurgie, Düsseldorf, Deutschland
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Hans-Jakob Steiger
- Heinrich-Heine-Universität, Universitätsklinikum, Klinik für Neurochirurgie, Düsseldorf, Deutschland
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Athanasios Petridis
- Heinrich-Heine-Universität, Universitätsklinikum, Klinik für Neurochirurgie, Düsseldorf, Deutschland
| Veröffentlicht: | 18. Juni 2018 |
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Gliederung
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Objective: Patients treated for ruptured aneurysms may be disabled physically and mentally. Quality of life (QoL) data after long-term follow-up is not routinely assessed. Recently, a scoring system to predict functional recovery and quality of life was reported (FRESH, Functional Recovery Expected after Subarachnoid Hemorrhage). We proposed to analyze FRESH scores with long-term QoL data of patients treated in our department.
Methods: Retrospective study of patients treated within the last six years (2011-2016) in a tertiary care center. Clinical data was derived from the digital hospital archive, FRESH- and FRESHquol (FRESH Quality of Life)-Score were calculated. Additionally, patients answered a modified Short Form-36 (allowing calculation of PSC, physical sum score and MCS, mental sum score) and participated in a Telephone Interview for Cognitive Status (TICS).
Results: 374 patients were identified. 55 (14.7%) of them had already died, 7.5% declined to participate. Of the remaining patients 138 of 321 (52.9%) answered, 9.3% had unknown contact data and the remaining 36.4% did not return the SF-36 after two requests for unknown reasons. Positive responses were proportionally spread over time of treatment. TICS was performed for 123 of 138 possible patients (93%). There were 67.1% women (mean age 56.8 years, SD ± 11.9) and 32.9% men (52.1 ± 12.3 years). Distribution of WFNS: Grade I (38.0%), Grade II (10.2%), Grade III (10.2%), Grade IV (14.4%) and Grade V (27.3%). FRESH-Scores were calculated for all patients having responded to SF-36: FRESH 1 (23.5%), FRESH 2 (22.5%), FRESH 3 (10.2%), FRESH 4 (8.6%), FRESH 5 (4.8%), FRESH 6 (24.1%), FRESH 7 (2.7%) and FRESH 8 (3.7%). For SF-36: PSC was above average in 21.9% and below average in 32.1%, MSC was above average in 5.8% and below in 45.3%. Analysis showed no correlation between FRESH, PSC and MSC, respectively. TICS analysis showed difficulties in memorization and word reproduction (74% had a score ≤ 5 / 10 points), orientation and repetition of a short sentence (impossible for 68.3%).
Conclusion: In this population calculated FRESH-scores and quality of life parameters assessed by SF-36 did not show good correlation. There was important bias due to a low rate of participation. This experience highlights the importance of prospective QoL assessment in patients treated for aneurysm rupture.
