gms | German Medical Science

69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

03.06. - 06.06.2018, Münster

Artikel

Artikel empfehlen

Cortical spreading depolarizations in lesional epilepsy surgery

Meeting Abstract

Suche in Medline nach

  • Daniel San Juan-Orta - National Institute of Neurology and Neurosurgery, Department of Clinical Research, Mexico City, Mexiko
  • Katía Márquez-González - National Institute of Neurology and Neurosurgery, Department of Clinical Research, Mexico City, Mexiko
  • Roberto Díaz-Peregrino - National Institute of Neurology and Neurosurgery, Department of Clinical Research, Mexico City, Mexiko
  • Mario Arturo Alonso-Vanegas - National Institute of Neurology and Neurosurgery, Department of Epilepsy Surgery, Mexico City, Mexiko
  • Edgar Santos - Universitätsklinikum Heidelberg, Klinik für Neurochirurgie, Heidelberg, Deutschland

Deutsche Gesellschaft für Neurochirurgie. 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie. Münster, 03.-06.06.2018. Düsseldorf: German Medical Science GMS Publishing House; 2018. DocV145

doi: 10.3205/18dgnc148, urn:nbn:de:0183-18dgnc1482

Veröffentlicht: 18. Juni 2018

© 2018 San Juan-Orta et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: Document the incidence of Spreading Depolarizations inlesional epilepsy surgery.

Methods: This is a prospective study with the goal to study 80 patients. We include adult patients undergoing elective craniotomy for epileptogenic supratentorial lesions lasting >2h. Electrocorticographic recordings were obtained from time of dural opening through the time of dural closure, using a standard 1 × 8 silver electrode coupled with a full-spectrum DC amplifier (0-45Hz, Notch:60Hz). We analyzed the clinical and socio-demographic characteristics. Detection of SDs was set as slow potential changes coupled with suppression of high-frequency ECoG propagating across the electrodes.

Results: From September to November 2017 we already included 16 patients, mean age 37(19-75) years-old, 50% male, underwent 4 callosotomies and 12 temporal lesionectomies (3 cortical dysplasia, 2 cavernomas, 5 gliomas and 2 dermoid cystic). All the patients had history of symptomatic epilepsy, none had postsurgical complications and only 2 patients post-callosotomy continued with seizures at 6 months of follow-up. Until now, we have not documented cases of SDs during these operations.

Conclusion: SDs were absent in this preliminary analysis during lesional epilepsy surgery.