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68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
7. Joint Meeting mit der Britischen Gesellschaft für Neurochirurgie (SBNS)

Deutsche Gesellschaft für Neurochirurgie (DGNC) e. V.

14. - 17. Mai 2017, Magdeburg

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Individuals with single or multiple intracranial aneurysms: What are the odds?

Meeting Abstract

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  • Ramazan Jabbarli - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik für Neurochirurgie, Essen, Deutschland
  • Marvin Darkwah Oppong - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik und Poliklinik für Neurochirurgie, Essen, Deutschland
  • Annika Herten - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik und Poliklinik für Neurochirurgie, Essen, Deutschland
  • Roman Frantsev - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik und Poliklinik für Neurochirurgie, Essen, Deutschland
  • Philipp Dammann - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik und Poliklinik für Neurochirurgie, Essen, Deutschland
  • Karsten H. Wrede - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik und Poliklinik für Neurochirurgie, Essen, Deutschland
  • Ulrich Sure - Universitätsklinikum Essen der Universität Duisburg-Essen, Klinik und Poliklinik für Neurochirurgie, Essen, Deutschland

Deutsche Gesellschaft für Neurochirurgie. Society of British Neurological Surgeons. 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS). Magdeburg, 14.-17.05.2017. Düsseldorf: German Medical Science GMS Publishing House; 2017. DocMi.02.07

doi: 10.3205/17dgnc368, urn:nbn:de:0183-17dgnc3687

Veröffentlicht: 9. Juni 2017

© 2017 Jabbarli et al.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). Lizenz-Angaben siehe http://creativecommons.org/licenses/by/4.0/.

Gliederung

Text

Objective: Patients with multiple intracranial aneurysms (MIA) are less common compared to patients with single aneurysms. However, the true incidences and the risk factors for MIA require proper evaluation. Moreover, the association between the presence of MIA and the risk / clinical course of subarachnoid hemorrhage (SAH) is still the matter in controversy.

Methods: This study was based on the institutional aneurysm database with 2451 individuals consecutively treated between January 2003 and June 2016. The database contains the radiographic characteristics of intracranial aneurysm(s) upon conventional angiography, as well as the demographic and clinical data of treated patients. The correlations with MIA were evaluated using univariate and multivariate analyses.

Results: 843 patients (34.4%) presented angiographically with MIA (ranging between 2 and 9 aneurysms). Most individuals suffered from two (n=541, 64.2%) or three intracranial aneurysms (n=191, 22.7%). Female (p<0.0001, adjusted odds ratio (aOR) =1.48) and elderly patients (with the cutoff at >45 years upon the receiver operating characteristic curve, p=0.004, aOR=1.35) were more likely to have MIA. There were no associations with the race (p=0.454), the history of SAH (p=0.843) and the size of the largest identified aneurysm (p=0.3065). The number of MIA independently correlated only with the female sex (p<0.0001). There was no statistical difference (p=0.8353) in the functional outcome of SAH patients with single and MIA.

Conclusion: The female sex is the major risk factor for MIA. The association between MIA and higher patients’ age may proceed from the development of new aneurysms over the lifetime. In our series, patients with MIA were not at a higher risk for SAH.